SCHEMBL9806487

SCHEMBL9806487

O=C(Oc1ccc(S(=O)(=O)c2ccc(O)cc2)cc1)c1ccccc1

nearest known ligand 0.58

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ELANE P08246 2/20 0.58
PARP10 Q53GL7 1/20 0.54
MAPT P10636 5/20 0.54
SMN1; SMN2 Q16637 1/20 0.54
PKM P14618 3/20 0.53
GAA P10253 1/20 0.53
KMT2A Q03164 7/20 0.51
TDP1 Q9NUW8 2/20 0.51
ALDH1A1 P00352 2/20 0.51
L3MBTL1 Q9Y468 1/20 0.51
MEN1 O00255 3/20 0.50
POLB P06746 1/20 0.50
RAB9A P51151 1/20 0.49
NSD2 O96028 1/20 0.46
ESR1 P03372 1/20 0.45
ESR2 Q92731 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11775909 0.93 PARP10 (0.61) ELANEPARP10MAPTSMN1; SMN2PKM
SCHEMBL31414978 0.90 PARP10 (0.65) PARP10MAPTSMN1; SMN2PKMGAA
SCHEMBL281981 0.88 PARP10 (0.67) PARP10MAPTPKMGAAKMT2A
SCHEMBL9806485 0.87 PARP10 (0.54) ELANEPARP10MAPTSMN1; SMN2PKM
SCHEMBL14725833 0.86 MAPT (0.69) PARP10MAPTSMN1; SMN2PKMKMT2A
SCHEMBL28822921 0.86 PARP10 (0.65) PARP10MAPTPKMGAAKMT2A
SCHEMBL5162040 0.86 PARP10 (0.70) ELANEPARP10MAPTSMN1; SMN2PKM
SCHEMBL9528723 0.86 SMN1; SMN2 (0.61) ELANEPARP10MAPTSMN1; SMN2PKM
SCHEMBL12123501 0.86 MAPT (0.72) ELANEPARP10MAPTSMN1; SMN2PKM
SCHEMBL26039005 0.84 SMN1; SMN2 (0.59) PARP10MAPTSMN1; SMN2PKMGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5021333-A Pivaloylacetanilide-type yellow coupler EASTMAN KODAK COMPANY (US) 1991-06-04 US disclosed