Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 9/20 | 0.63 |
| ▸ | CA1 | P00915 | 9/20 | 0.63 |
| ▸ | CA2 | P00918 | 9/20 | 0.63 |
| ▸ | CA9 | Q16790 | 9/20 | 0.63 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | RARB | P10826 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9305629 | 0.96 | CA12 (0.63) | CA12CA1CA2CA9TSHR | |
| SCHEMBL9806621 | 0.96 | CA12 (0.63) | CA12CA1CA2CA9TSHR | |
| SCHEMBL28759999 | 0.88 | CA12 (0.71) | CA12CA1CA2CA9TSHR | |
| SCHEMBL671987 | 0.87 | CA12 (0.82) | CA12CA1CA2CA9TSHR | |
| SCHEMBL9306529 | 0.83 | CA12 (0.57) | CA12CA1CA2CA9TSHR | |
| SCHEMBL9806528 | 0.83 | CA12 (0.57) | CA12CA1CA2CA9TSHR | |
| SCHEMBL672928 | 0.82 | CA12 (0.82) | CA12CA1CA2CA9TSHR | |
| Potassium Ion SCHEMBL229878 | 0.82 | — | — | |
| SCHEMBL153267 | 0.82 | CA12 (0.82) | CA12CA1CA2CA9TSHR | |
| SCHEMBL11458459 | 0.82 | CA12 (0.82) | CA12CA1CA2CA9TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5035815-A | Synergistic, antiwear | EXXON RESEARCH AND ENGINEERING COMPANY (US) | 1991-07-30 | — | — | US | disclosed |
| US-5034142-A | Wear resistant compositions for engines | EXXON RESEARCH AND ENGINEERING COMPANY (US) | 1991-07-23 | — | — | US | disclosed |