Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.39 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL902070 | 1.00 | NPSR1 (0.47) | NPSR1MAPTCYP4F2CYP4A11CYP3A4 | |
| SCHEMBL7440708 | 1.00 | NPSR1 (0.47) | NPSR1MAPTCYP4F2CYP4A11CYP3A4 | |
| SCHEMBL5719495 | 0.98 | NPSR1 (0.45) | NPSR1MAPTCYP4F2CYP4A11CYP3A4 | |
| SCHEMBL3681568 | 0.98 | NPSR1 (0.45) | NPSR1MAPTCYP4F2CYP4A11CYP3A4 | |
| SCHEMBL757321 | 0.98 | NPSR1 (0.48) | NPSR1MAPTCYP4F2CYP4A11CYP3A4 | |
| SCHEMBL230257 | 0.93 | NPSR1 (0.43) | NPSR1MAPTCYP4F2CYP4A11CYP3A4 | |
| SCHEMBL594374 | 0.88 | NPSR1 (0.52) | NPSR1MAPTCYP4F2CYP4A11CYP3A4 | |
| SCHEMBL4870814 | 0.88 | NPSR1 (0.52) | NPSR1MAPTCYP4F2CYP4A11CYP3A4 | |
| SCHEMBL9806699 | 0.88 | NPSR1 (0.52) | NPSR1MAPTCYP4F2CYP4A11CYP3A4 | |
| SCHEMBL71320 | 0.88 | NPSR1 (0.41) | NPSR1MAPTCYP4F2CYP4A11CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5075492-A | METHOD OF MANUFACTURING CYCLOOCTANEDICARBOXYLIC ACID DIESTERS | HUELS AKTIENGESELLSCHAFT (DE) | 1991-12-24 | — | — | US | disclosed |