Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 8/20 | 0.76 |
| ▸ | CYSLTR1 | Q9Y271 | 8/20 | 0.76 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.55 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8998138 | 0.99 | CYSLTR2 (0.77) | CYSLTR2CYSLTR1PLA2G4AEPHX2PPARG | |
| SCHEMBL8998287 | 0.92 | CYSLTR2 (0.74) | CYSLTR2CYSLTR1PLA2G4AEPHX2PPARG | |
| SCHEMBL9806757 | 0.91 | CYSLTR2 (0.72) | CYSLTR2CYSLTR1PLA2G4AEPHX2PPARG | |
| Ici-198615 SCHEMBL9806720 | 0.86 | CYSLTR1 (1.00) | CYSLTR2CYSLTR1PLA2G4AEPHX2PPARG | |
| Ici-198615 SCHEMBL29465033 | 0.86 | CYSLTR1 (1.00) | CYSLTR2CYSLTR1PLA2G4AEPHX2PPARG | |
| Ici-198615 SCHEMBL31060498 | 0.86 | CYSLTR1 (1.00) | CYSLTR2CYSLTR1PLA2G4AEPHX2PPARG | |
| SCHEMBL8998206 | 0.86 | CYSLTR2 (0.70) | CYSLTR2CYSLTR1PLA2G4AEPHX2PPARG | |
| SCHEMBL9479016 | 0.86 | CYSLTR2 (0.61) | CYSLTR2CYSLTR1EPHX2NR1H4 | |
| SCHEMBL8998282 | 0.85 | CYSLTR2 (0.69) | CYSLTR2CYSLTR1PLA2G4AEPHX2PPARG | |
| SCHEMBL8998205 | 0.84 | CYSLTR1 (0.76) | CYSLTR2CYSLTR1PLA2G4AEPHX2PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4997844-A | Compounds for the treatment of allergic or inflammatory diseases or shock conditions | ICI AMERICAS INC. (US) | 1991-03-05 | — | — | US | disclosed |
| EP-0179619-B1 | HETEROCYCLIC AMIDES | ICI AMERICAS INC. (US) | 1990-09-05 | — | — | EP | disclosed |
| EP-0179619-A1 | Heterocyclic amides | ICI AMERICAS INC. (US) | 1986-04-30 | — | — | EP | disclosed |