Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 4/20 | 0.58 |
| ▸ | ESR1 | P03372 | 1/20 | 0.52 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | CA9 | Q16790 | 3/20 | 0.49 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.49 |
| ▸ | PTPRC | P08575 | 2/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | CES1 | P23141 | 1/20 | 0.47 |
| ▸ | S100A4 | P26447 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | ELANE | P08246 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9807393 | 0.85 | CA12 (0.64) | CA12ESR1ESR2ALDH1A1RECQL | |
| SCHEMBL9807432 | 0.84 | CA12 (0.55) | CA12ESR1ESR2ALDH1A1RECQL | |
| SCHEMBL9113889 | 0.84 | CA12 (0.72) | CA12ESR1ESR2ALDH1A1RECQL | |
| SCHEMBL9807445 | 0.82 | CA12 (0.53) | CA12ESR1ESR2ALDH1A1RECQL | |
| SCHEMBL9807402 | 0.82 | CA12 (0.67) | CA12ESR1ESR2ALDH1A1CA9 | |
| SCHEMBL9807407 | 0.82 | CA12 (0.55) | CA12ESR1ESR2ALDH1A1RECQL | |
| SCHEMBL9807437 | 0.81 | ESR1 (0.50) | CA12ESR1ESR2ALDH1A1RECQL | |
| SCHEMBL9807389 | 0.80 | SCN2A (0.63) | CA12ESR1RECQLMEN1KMT2A | |
| SCHEMBL9807401 | 0.79 | CA12 (0.59) | CA12ESR1ESR2MEN1KMT2A | |
| SCHEMBL9807433 | 0.78 | CA12 (0.53) | CA12ESR1ESR2ALDH1A1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4990627-A | Polyetherimides and their production | ETHYL CORPORATION (US) | 1991-02-05 | — | — | US | claimed |
| US-4994545-A | Polyetherimide | ETHYL CORPORATION (US) | 1991-02-19 | — | — | US | disclosed |
| US-4990627-A | Polyetherimides and their production | ETHYL CORPORATION (US) | 1991-02-05 | — | — | US | disclosed |