Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 6/20 | 0.52 |
| ▸ | PTPN7 | P35236 | 5/20 | 0.52 |
| ▸ | RECQL | P46063 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4631522 | 0.90 | HMGCR (0.42) | HMGCRPTPN7RECQLTDP1KDM4E | |
| SCHEMBL4551760 | 0.84 | EPHX2 (0.46) | HMGCRPTPN7RECQLTDP1KDM4E | |
| SCHEMBL11680738 | 0.79 | GRIK1 (0.31) | — | |
| SCHEMBL9807792 | 0.78 | PTPN7 (0.43) | HMGCRPTPN7RECQLTDP1KDM4E | |
| SCHEMBL29843020 | 0.78 | PTPN7 (0.43) | HMGCRPTPN7RECQLTDP1KDM4E | |
| SCHEMBL23040316 | 0.76 | PTPN7 (0.61) | HMGCRPTPN7RECQLTDP1KDM4E | |
| SCHEMBL10796010 | 0.76 | PTPN7 (0.61) | HMGCRPTPN7RECQLTDP1KDM4E | |
| SCHEMBL1523678 | 0.76 | PTPN7 (0.61) | HMGCRPTPN7RECQLTDP1KDM4E | |
| SCHEMBL11066113 | 0.76 | PTPN7 (0.61) | HMGCRPTPN7RECQLTDP1KDM4E | |
| SCHEMBL513302 | 0.76 | PTPN7 (0.61) | HMGCRPTPN7RECQLTDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0323163-B1 | SHIFT-FEEL DURABILITY ENHANCEMENT | ETHYL PETROLEUM ADDITIVES, INC. (US) | 1991-05-29 | — | — | EP | disclosed |
| EP-0323163-A1 | Shift-feel Durability enhancement | ETHYL PETROLEUM ADDITIVES, INC. (US) | 1989-07-05 | — | — | EP | disclosed |
| US-4795583-A | FRICTION MODIFIER FOR AUTOMATIC TRANSMISSION FLUIDS CONTAINING AN ALIPHATIC TERTIARY AMINE, ALIPHATIC DIAMINE AND-OR N-SUBSTITUTED DIALKANOLAMINE | ETHYL PETROLEUM ADDITIVES, INC. (US) | 1989-01-03 | — | — | US | disclosed |