Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 16/20 | 0.71 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.71 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11587655 | 0.93 | HRH3 (0.63) | HRH3KCNH2CYP2C9CYP3A4 | |
| SCHEMBL27508210 | 0.91 | HRH3 (0.61) | HRH3KCNH2CYP2C9CYP3A4 | |
| SCHEMBL10770845 | 0.90 | HRH3 (0.60) | HRH3KCNH2CYP2C9CYP3A4 | |
| SCHEMBL12835099 | 0.90 | HRH3 (0.60) | HRH3KCNH2CYP2C9CYP3A4 | |
| SCHEMBL5556221 | 0.89 | HRH3 (0.63) | HRH3KCNH2CYP2C9CYP3A4KDM4E | |
| SCHEMBL28063059 | 0.88 | HRH3 (0.57) | HRH3KCNH2CYP2C9 | |
| SCHEMBL8682954 | 0.87 | HRH3 (0.60) | HRH3KCNH2CYP2C9CYP3A4NFE2L2 | |
| SCHEMBL10798982 | 0.87 | HRH3 (0.60) | HRH3KCNH2CYP2C9CYP3A4 | |
| SCHEMBL8683784 | 0.87 | HRH3 (0.60) | HRH3KCNH2CYP2C9CYP3A4NFE2L2 | |
| SCHEMBL4339149 | 0.87 | HRH3 (0.60) | HRH3KCNH2CYP2C9CYP3A4NFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4985393-A | Bis/hydroxyphenylthio/ Compounds | KANZAKI PAPER MANUFACTURING CO., LTD. (JP) | 1991-01-15 | — | — | US | disclosed |
| EP-0373561-A2 | Heat sensitive recording material | KANZAKI PAPER MANUFACTURING CO., LTD. (JP) | 1990-06-20 | — | — | EP | disclosed |