Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B2 | P37059 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.39 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9808295 | 0.95 | KDM4E (0.45) | HSD17B2MAPTGAAKDM4EPOLB | |
| SCHEMBL9808059 | 0.91 | GAA (0.40) | MAPTGAAKDM4EMEN1KMT2A | |
| SCHEMBL9808190 | 0.87 | HDAC6 (0.49) | HSD17B2MAPTGAAKDM4EPOLB | |
| SCHEMBL9808040 | 0.86 | MEN1 (0.39) | MAPTGAAKDM4EPOLBMEN1 | |
| SCHEMBL9808029 | 0.86 | MEN1 (0.39) | MAPTGAAKDM4EPOLBMEN1 | |
| SCHEMBL9808041 | 0.85 | KDM4E (0.46) | HSD17B2MAPTGAAKDM4EPOLB | |
| SCHEMBL9808171 | 0.85 | KDM4E (0.46) | HSD17B2MAPTGAAKDM4EPOLB | |
| SCHEMBL9808284 | 0.84 | ATM (0.38) | MAPTGAAKDM4EMEN1KMT2A | |
| SCHEMBL9808055 | 0.84 | KDM4E (0.45) | HSD17B2GAAKDM4EPOLBHDAC6 | |
| SCHEMBL9808103 | 0.83 | KDM4E (0.48) | HSD17B2MAPTGAAKDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4985393-A | Bis/hydroxyphenylthio/ Compounds | KANZAKI PAPER MANUFACTURING CO., LTD. (JP) | 1991-01-15 | — | — | US | disclosed |