Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | FDPS | P14324 | 10/20 | 0.44 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.44 |
| ▸ | GGPS1 | O95749 | 6/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.39 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8685667 | 1.00 | TSHR (0.50) | TSHRTHRBALDH1A1FDPSSMPD1 | |
| SCHEMBL5178216 | 1.00 | TSHR (0.50) | TSHRTHRBALDH1A1FDPSSMPD1 | |
| SCHEMBL8685461 | 1.00 | TSHR (0.50) | TSHRTHRBALDH1A1FDPSSMPD1 | |
| SCHEMBL28639329 | 1.00 | TSHR (0.50) | TSHRTHRBALDH1A1FDPSSMPD1 | |
| SCHEMBL8687488 | 1.00 | TSHR (0.50) | TSHRTHRBALDH1A1FDPSSMPD1 | |
| SCHEMBL7613996 | 1.00 | TSHR (0.50) | TSHRTHRBALDH1A1FDPSSMPD1 | |
| Ammonia Solution, Strong SCHEMBL1094258 | 0.97 | TSHR (0.47) | TSHRTHRBALDH1A1FDPSSMPD1 | |
| Ammonia Solution, Strong SCHEMBL11831912 | 0.97 | TSHR (0.47) | TSHRTHRBALDH1A1FDPSSMPD1 | |
| Ammonia Solution, Strong SCHEMBL11830969 | 0.97 | TSHR (0.47) | TSHRTHRBALDH1A1FDPSSMPD1 | |
| Ammonia Solution, Strong SCHEMBL11832302 | 0.97 | TSHR (0.47) | TSHRTHRBALDH1A1FDPSSMPD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0224179-B1 | PROCESS FOR THE MANUFACTURE OF POLYMERS CONTAINING REACTIVE END GROUPS | BAYER AG (DE) | 1991-05-15 | — | — | EP | disclosed |
| US-4740572-A | Process for the production of polymers containing reactive terminal groups | BAYER AKTIENGESELLSCHAFT (DE) | 1988-04-26 | — | — | US | disclosed |
| EP-0224759-A2 | Manufacture of polymers by cationic polymerization | BAYER AG (DE) | 1987-06-10 | — | — | EP | disclosed |
| EP-0224179-A2 | Process for the manufacture of polymers containing reactive end groups | BAYER AG (DE) | 1987-06-03 | — | — | EP | disclosed |
| US-4611037-A | HALOGEN END GROUPS | BAYER AKTIENGESELLSCHAFT (DE) | 1986-09-09 | — | — | US | disclosed |
| EP-0175122-A2 | Process for the manufacture of polymers containing reactive end groups | BAYER AG (DE) | 1986-03-26 | — | — | EP | disclosed |