Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 1/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA3 | P07451 | 2/20 | 0.33 |
| ▸ | CA4 | P22748 | 2/20 | 0.33 |
| ▸ | CA6 | P23280 | 2/20 | 0.33 |
| ▸ | CA5A | P35218 | 2/20 | 0.33 |
| ▸ | CA7 | P43166 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.33 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.33 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.33 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12295827 | 0.89 | — | — | |
| SCHEMBL756509 | 0.89 | — | — | |
| SCHEMBL16351273 | 0.87 | — | — | |
| SCHEMBL755110 | 0.87 | — | — | |
| SCHEMBL8979991 | 0.87 | GSR (0.48) | GSRTRPV1TRPA1RNPEPNFKB1 | |
| SCHEMBL8979967 | 0.87 | GSR (0.48) | GSRTRPV1TRPA1RNPEPNFKB1 | |
| SCHEMBL9809166 | 0.85 | GSR (0.43) | GSRTRPV1TRPA1RNPEPNFKB1 | |
| Hydrochloric Acid SCHEMBL7610353 | 0.84 | GSR (0.46) | GSRTRPV1TRPA1RNPEPNFKB1 | |
| SCHEMBL16359908 | 0.81 | — | — | |
| SCHEMBL40004 | 0.81 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0167310-B1 | PLATINUM CO-ORDINATION COMPOUNDS | JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) | 1991-05-29 | — | — | EP | disclosed |
| US-4956454-A | AMINE LIGANDS BONDED TO PLATINUM AND MONOCLONAL ANTIBODIES TO FORM COORDINATION COMPOUNDS | JOHNSON MATTHEY PLC (GB) | 1990-09-11 | — | — | US | disclosed |
| US-4760155-A | Platinum co-ordination compounds | JOHNSON MATTHEY PLC (GB) | 1988-07-26 | — | — | US | disclosed |
| EP-0167310-A2 | Platinum co-ordination compounds | JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) | 1986-01-08 | — | — | EP | disclosed |