Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2D | O15399 | 5/20 | 0.44 |
| ▸ | GRIN3B | O60391 | 5/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 5/20 | 0.44 |
| ▸ | GRIN2A | Q12879 | 5/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 5/20 | 0.44 |
| ▸ | GRIN2C | Q14957 | 5/20 | 0.44 |
| ▸ | GRIN3A | Q8TCU5 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24520252 | 1.00 | GRIN2D (0.44) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL24520256 | 1.00 | GRIN2D (0.44) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL24548567 | 1.00 | GRIN2D (0.44) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL9810413 | 0.85 | MEN1 (0.44) | MEN1NPC1RAB9AKMT2AALDH1A1 | |
| SCHEMBL9810598 | 0.85 | MEN1 (0.44) | MEN1NPC1RAB9AKMT2AALDH1A1 | |
| SCHEMBL28380069 | 0.84 | KMT2A (0.39) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL10619746 | 0.82 | MEN1 (0.40) | MEN1NPC1RAB9AKMT2AALDH1A1 | |
| SCHEMBL10619751 | 0.82 | MEN1 (0.40) | MEN1NPC1RAB9AKMT2AALDH1A1 | |
| SCHEMBL1068201 | 0.82 | MEN1 (0.40) | MEN1NPC1RAB9AKMT2AALDH1A1 | |
| SCHEMBL10622319 | 0.82 | MEN1 (0.40) | MEN1NPC1RAB9AKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0284084-B1 | INTENSELY SWEET L-ASPARTYL-3-(BICYCLOALKYL)-L-ALANINE ALKYL ESTERS | THE COCA-COLA COMPANY (US) | 1991-06-26 | — | — | EP | disclosed |
| US-4788069-A | SWEETENING EDIBLE FOODS AND BEVERAGES | THE COCA-COLA COMPANY (US) | 1988-11-29 | — | — | US | disclosed |
| WO-1988007522-A1 | INTENSELY SWEET L-ASPARTYL-3-(BICYCLOALKYL)-L-ALANINE ALKYL ESTERS | THE COCA-COLA COMPANY (US) | 1988-10-06 | — | — | WO | disclosed |
| EP-0284084-A2 | Intensely sweet L-aspartyl-3-(Bicycloalkyl)-L-alanine alkyl esters | THE COCA-COLA COMPANY (US) | 1988-09-28 | — | — | EP | disclosed |