SCHEMBL9810567

SCHEMBL9810567

Nc1cccc(C=CC=Cc2cccc(N)c2)c1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 7/20 0.71
MAOB P27338 3/20 0.71
MAOA P21397 3/20 0.71
NPC1 O15118 1/20 0.61
MAPT P10636 1/20 0.61
GFER P55789 1/20 0.61
NPSR1 Q6W5P4 1/20 0.59
CYP3A4 P08684 1/20 0.52
CASP1 P29466 1/20 0.52
RECQL P46063 1/20 0.52
APP P05067 1/20 0.48
KDM1A O60341 2/20 0.46
ALDH1A1 P00352 3/20 0.43
LMNA P02545 1/20 0.43
KDM4E B2RXH2 1/20 0.43
ENPP2 Q13822 1/20 0.43
CA12 O43570 1/20 0.42
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
CA7 P43166 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9810564 1.00 CYP19A1 (0.71) CYP19A1MAOBMAOANPC1MAPT
SCHEMBL2774526 0.90 CYP19A1 (0.86) CYP19A1MAOBMAOANPC1MAPT
SCHEMBL29664559 0.90 CYP19A1 (0.86) CYP19A1MAOBMAOANPC1MAPT
SCHEMBL2774532 0.90 CYP19A1 (0.86) CYP19A1MAOBMAOANPC1MAPT
SCHEMBL20825106 0.87 CYP19A1 (0.61) CYP19A1MAOBMAOANPC1MAPT
SCHEMBL22350268 0.87 CYP19A1 (0.61) CYP19A1MAOBMAOANPC1MAPT
SCHEMBL11288405 0.85 CYP19A1 (0.91) CYP19A1MAOBMAOANPC1MAPT
SCHEMBL11288404 0.85 CYP19A1 (0.91) CYP19A1MAOBMAOANPC1MAPT
SCHEMBL2775801 0.83 CYP19A1 (1.00) CYP19A1MAOBMAOANPC1MAPT
SCHEMBL29084173 0.83 CYP19A1 (1.00) CYP19A1MAOBMAOANPC1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008083258-A1 POLYIMIDE/COPOLYIMIDE FILMS WITH LOW GLASS TRANSITION TEMPERATURE FOR USE AS HOT MELT ADHESIVES ADAPTIVENERGY, LLC. (US) 2008-07-10 WO disclosed
EP-0188675-B1 ULTRATHIN POLYMERIC IMINE FILMS AND PROCESS FOR MAKING THE SAME Research Development Corporation of Japan (JP) 1991-06-05 EP disclosed
US-4966743-A Process for making ultrathin polymeric imine films RESEARCH DEVELOPMENT CORPORATION OF JAPAN (JP) 1990-10-30 US disclosed
US-4778720-A PRODUCT OF DIAMINE AND DIIMINE SCHIFF BASE; SEMICONDUCTORS RESEARCH DEV. CORP. OF JAPAN (JP) 1988-10-18 US disclosed
US-4681799-A Ultrathin polymeric imine films and process for making the same RESEARCH DEVELOPMENT CORP. OF JAPAN (JP) 1987-07-21 US disclosed
EP-0188675-A1 Ultrathin polymeric imine films and process for making the same Research Development Corporation of Japan (JP) 1986-07-30 EP disclosed