Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8491509 | 0.74 | CYP3A4 (0.33) | ALDH1A1HPGDHSD17B10TDP1 | |
| SCHEMBL18807648 | 0.71 | POLB (0.38) | KDM4EALDH1A1POLBMAPTHPGD | |
| SCHEMBL27666975 | 0.70 | MEN1 (0.35) | KDM4EALDH1A1TDP1 | |
| SCHEMBL19561876 | 0.70 | — | — | |
| SCHEMBL19752505 | 0.70 | — | — | |
| SCHEMBL23347007 | 0.70 | — | — | |
| SCHEMBL6228672 | 0.69 | — | — | |
| SCHEMBL28500583 | 0.68 | MAPT (0.33) | KDM4EUSP2ALDH1A1POLBMAPT | |
| SCHEMBL18790353 | 0.67 | POLB (0.32) | ALDH1A1POLB | |
| SCHEMBL28844134 | 0.66 | TAAR1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0258095-B1 | DECAHYDROQUINOLINE DERIVATIVES, METHOD FOR THEIR PREPARATION AND INTERMEDIATES THEREOF, THEIR USE AS MEDICAMENTS AND THEIR PHARMACEUTICAL COMPOSITIONS | ROUSSEL-UCLAF (FR) | 1991-06-12 | — | — | EP | disclosed |
| EP-0258095-A1 | Decahydroquinoline derivatives, method for their preparation and intermediates thereof, their use as medicaments and their pharmaceutical compositions | ROUSSEL-UCLAF (FR) | 1988-03-02 | — | — | EP | disclosed |