Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | CNR2 | P34972 | 7/20 | 0.47 |
| ▸ | CNR1 | P21554 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 4/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | KIF11 | P52732 | 1/20 | 0.37 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2028907 | 0.87 | CNR2 (0.56) | MAPTNPC1RAB9ACNR2CNR1 | |
| SCHEMBL28585334 | 0.84 | CNR2 (0.66) | MAPTNPC1RAB9ACNR2CNR1 | |
| SCHEMBL22043106 | 0.84 | CNR2 (0.66) | MAPTNPC1RAB9ACNR2CNR1 | |
| SCHEMBL29193377 | 0.84 | CNR2 (0.66) | MAPTNPC1RAB9ACNR2CNR1 | |
| SCHEMBL24272949 | 0.82 | MAPT (0.50) | MAPTNPC1RAB9ACNR2CNR1 | |
| SCHEMBL10803424 | 0.82 | MAPT (0.46) | MAPTNPC1RAB9ACNR2CNR1 | |
| SCHEMBL18930278 | 0.81 | TSHR (0.46) | CNR2CNR1ESR1ESR2TSHR | |
| SCHEMBL582676 | 0.81 | NPC1 (0.77) | MAPTNPC1RAB9ACNR2CNR1 | |
| SCHEMBL13523937 | 0.79 | ESR1 (0.61) | MAPTNPC1RAB9ACNR2CNR1 | |
| SCHEMBL23616384 | 0.79 | CNR2 (0.44) | MAPTNPC1RAB9ACNR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11040028-B2 | Penicinotam derivative, preparation method and use thereof | OCEAN UNIVERSITY OF CHINA (CN) | 2021-06-22 | — | — | US | disclosed |
| US-20110080547-A1 | LIQUID CRYSTAL DISPLAY DEVICE | JAPAN DISPLAY EAST INC. (JP) | 2011-04-07 | — | — | US | disclosed |
| EP-0257882-B1 | N-PHENYL BUTENAMIDES WITH PHARMACEUTICAL PROPERTIES | LILLY INDUSTRIES LIMITED (GB) | 1991-07-24 | — | — | EP | disclosed |
| US-4892963-A | IMMUNE DISEASES | LILLY INDUSTRIES LIMITED (GB) | 1990-01-09 | — | — | US | disclosed |
| EP-0257882-A1 | N-Phenyl butenamides with pharmaceutical properties | LILLY INDUSTRIES LIMITED (GB) | 1988-03-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11040028-B2 | Penicinotam derivative, preparation method and use thereof | TPMT, MAPT, TLR4 | MAPT 2/4885NPC1 1374/4885RAB9A 3833/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.