Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.42 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.42 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.42 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.42 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.42 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.41 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26714275 | 0.82 | POLB (0.55) | POLBALDH1A1NPSR1PSEN1PSEN2 | |
| SCHEMBL31722127 | 0.82 | POLB (0.55) | POLBALDH1A1NPSR1PSEN1PSEN2 | |
| SCHEMBL13032659 | 0.81 | POLB (0.57) | POLBALDH1A1NPSR1MEN1KMT2A | |
| SCHEMBL3578965 | 0.80 | POLB (0.55) | POLBALDH1A1NPSR1MEN1KMT2A | |
| SCHEMBL14012812 | 0.80 | POLB (0.55) | POLBALDH1A1NPSR1MEN1KMT2A | |
| SCHEMBL9586427 | 0.80 | POLB (0.55) | POLBALDH1A1NPSR1MEN1KMT2A | |
| SCHEMBL8697857 | 0.80 | POLB (0.55) | POLBALDH1A1NPSR1MEN1KMT2A | |
| SCHEMBL12164616 | 0.80 | POLB (0.55) | POLBALDH1A1NPSR1MEN1KMT2A | |
| SCHEMBL8660402 | 0.80 | POLB (0.55) | POLBALDH1A1NPSR1MEN1KMT2A | |
| SCHEMBL31721749 | 0.79 | POLB (0.54) | POLBALDH1A1NPSR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-3112962-A | — | — | None | — | — | JP | disclosed |
| JP-H03112962-A | NEW HYDROXYPYRROLIDINE COMPOUND, INTERMEDIATE FOR PRODUCTION THEREOF AND PRODUCTION THEREOF | DAISO CO LTD | 1991-05-14 | — | — | JP | disclosed |