Acetic Acid

Acetic Acid

SCHEMBL9812829

C=C(CCCN(CC)CC)C(=O)O.CC(=O)O

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PAOX Q6QHF9 1/20 0.42
APOBEC3A P31941 1/20 0.38
APOBEC3G Q9HC16 1/20 0.38
ALDH1A1 P00352 4/20 0.38
KDM5A P29375 1/20 0.36
KDM4C Q9H3R0 1/20 0.36
GAA P10253 1/20 0.36
TBXAS1 P24557 2/20 0.35
LMNA P02545 2/20 0.33
KDM4E B2RXH2 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2D6 P10635 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
THRB P10828 1/20 0.32
FNTA P49354 1/20 0.32
FNTB P49356 1/20 0.32
PGGT1B P53609 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
MAOB P27338 1/20 0.32
BCHE P06276 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21173 0.96 PAOX (0.41) PAOXAPOBEC3AAPOBEC3GALDH1A1KDM5A
Methacrylic Acid SCHEMBL15637277 0.94 PAOX (0.41) PAOXAPOBEC3AAPOBEC3GALDH1A1KDM5A
Hydrochloric Acid SCHEMBL1396446 0.94 PAOX (0.40) PAOXAPOBEC3AAPOBEC3GALDH1A1KDM5A
Chloromethane SCHEMBL2515652 0.92 PAOX (0.39) PAOXAPOBEC3AAPOBEC3GALDH1A1KDM5A
SCHEMBL11417088 0.92 GAA (0.39) PAOXAPOBEC3AAPOBEC3GALDH1A1KDM5A
SCHEMBL6143382 0.92 PAOX (0.39) PAOXAPOBEC3AAPOBEC3GALDH1A1KDM5A
SCHEMBL2373700 0.92 KDM5A (0.42) PAOXAPOBEC3AAPOBEC3GALDH1A1KDM5A
SCHEMBL15233992 0.91 PAOX (0.38) PAOXAPOBEC3AAPOBEC3GALDH1A1KDM5A
Ethyl Chloride SCHEMBL5447583 0.91 PAOX (0.38) PAOXAPOBEC3AAPOBEC3GALDH1A1KDM5A
SCHEMBL20935 0.90 KDM5A (0.44) PAOXAPOBEC3AAPOBEC3GALDH1A1KDM5A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4366864-A1 METHOD FOR PRODUCING A MULTI-CAPILLARY LINING SEPARATIVE (FR) 2024-05-15 EP claimed
WO-2023281209-A1 METHOD FOR PRODUCING A MULTI-CAPILLARY LINING SEPARATIVE (FR) 2023-01-12 WO claimed
EP-4366864-A1 METHOD FOR PRODUCING A MULTI-CAPILLARY LINING SEPARATIVE (FR) 2024-05-15 EP disclosed
WO-2023281209-A1 METHOD FOR PRODUCING A MULTI-CAPILLARY LINING SEPARATIVE (FR) 2023-01-12 WO disclosed
EP-0208421-B1 FLUOROPOLYMER COMPOSITIONS, THEIR PREPARATION AND USE E.I. DU PONT DE NEMOURS AND COMPANY (US) 1991-07-17 EP disclosed
EP-0208421-A2 Fluoropolymer compositions, their preparation and use E.I. DU PONT DE NEMOURS AND COMPANY (US) 1987-01-14 EP disclosed
US-4595518-A Oil and water repellency E. I. DU PONT DE NEMOURS AND COMPANY (US) 1986-06-17 US disclosed
US-4070283-A Controlled surface porosity particles and a method for their production E. I. DU PONT DE NEMOURS AND COMPANY (US) 1978-01-24 US disclosed