Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 2/20 | 0.73 |
| ▸ | TSHR | P16473 | 2/20 | 0.73 |
| ▸ | MAPT | P10636 | 2/20 | 0.73 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.73 |
| ▸ | POLB | P06746 | 1/20 | 0.73 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.73 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.73 |
| ▸ | RECQL | P46063 | 1/20 | 0.73 |
| ▸ | BLM | P54132 | 1/20 | 0.73 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.73 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.73 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.73 |
| ▸ | CES2 | O00748 | 2/20 | 0.68 |
| ▸ | CES1 | P23141 | 2/20 | 0.68 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | PARP10 | Q53GL7 | 3/20 | 0.55 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.55 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.55 |
| ▸ | MAP4K4 | O95819 | 3/20 | 0.55 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzamide SCHEMBL28270473 | 0.93 | TSHR (0.76) | PARP1TSHRMAPTL3MBTL1POLB | |
| SCHEMBL77931 | 0.91 | MAP4K4 (0.62) | PARP1TSHRMAPTL3MBTL1POLB | |
| SCHEMBL29959902 | 0.91 | MAP4K4 (0.62) | PARP1TSHRMAPTL3MBTL1POLB | |
| Phenol SCHEMBL28467553 | 0.90 | PARP1 (0.58) | PARP1TSHRMAPTL3MBTL1POLB | |
| Iodide SCHEMBL19056893 | 0.88 | MAP4K4 (0.60) | PARP1TSHRMAPTL3MBTL1POLB | |
| Hydrochloric Acid SCHEMBL28021646 | 0.88 | MAP4K4 (0.60) | PARP1TSHRMAPTL3MBTL1POLB | |
| Hydrochloric Acid SCHEMBL409480 | 0.88 | MAP4K4 (0.60) | PARP1TSHRMAPTL3MBTL1POLB | |
| Hydrochloric Acid SCHEMBL3772040 | 0.88 | MAP4K4 (0.60) | PARP1TSHRMAPTL3MBTL1POLB | |
| Bromide SCHEMBL28799121 | 0.88 | MAP4K4 (0.60) | PARP1TSHRMAPTL3MBTL1POLB | |
| Terephthalamide SCHEMBL27486747 | 0.88 | PARP1 (0.94) | PARP1TSHRMAPTL3MBTL1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0299328-B1 | REACTIVE DYES | BAYER AG (DE) | 1991-07-10 | — | — | EP | disclosed |
| EP-0271656-B1 | REACTIVE AMINO ALKOXY-TRIPHENE DIOXAZINE DYES | BAYER AG (DE) | 1990-08-01 | — | — | EP | disclosed |
| US-4874857-A | FIBER-REACTIVE DYES | BAYER AKTIENGESELLSCHAFT (DE) | 1989-10-17 | — | — | US | disclosed |
| EP-0299328-A2 | Reactive dyes | BAYER AG (DE) | 1989-01-18 | — | — | EP | disclosed |
| EP-0271656-A1 | Reactive amino alkoxy-triphene dioxazine dyes | BAYER AG (DE) | 1988-06-22 | — | — | EP | disclosed |