Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | POLB | P06746 | 3/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11093553 | 1.00 | KDM4E (0.52) | KDM4EHSD17B10MAPTALDH1A1POLB | |
| SCHEMBL9813351 | 1.00 | KDM4E (0.52) | KDM4EHSD17B10MAPTALDH1A1POLB | |
| SCHEMBL11091255 | 1.00 | KDM4E (0.52) | KDM4EHSD17B10MAPTALDH1A1POLB | |
| SCHEMBL22324061 | 0.98 | MAPT (0.52) | KDM4EHSD17B10MAPTALDH1A1POLB | |
| SCHEMBL22323590 | 0.98 | MAPT (0.52) | KDM4EHSD17B10MAPTALDH1A1POLB | |
| SCHEMBL6028694 | 0.98 | MAPT (0.52) | KDM4EHSD17B10MAPTALDH1A1POLB | |
| SCHEMBL3830715 | 0.92 | MAPT (0.47) | KDM4EHSD17B10MAPTALDH1A1POLB | |
| SCHEMBL27486927 | 0.90 | MAPT (0.46) | KDM4EHSD17B10MAPTALDH1A1POLB | |
| SCHEMBL29730977 | 0.84 | — | — | |
| SCHEMBL28392227 | 0.83 | MAPT (0.42) | KDM4EHSD17B10MAPTALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0230499-B1 | PROCESS FOR PREPARING MACROCYCLIC KETONES | NIPPON MINING COMPANY LIMITED (JP) | 1991-07-03 | — | — | EP | disclosed |
| US-4700007-A | PERFORMING ACYLOIN CONDENSATION AND REDUCTION REACTIONS IN ONE WATER-IMMISCIBLE SOLVENT SOLUTION | NIPPON MINING CO., LTD. (JP) | 1987-10-13 | — | — | US | disclosed |
| EP-0230499-A1 | Process for preparing macrocyclic ketones | NIPPON MINING COMPANY LIMITED (JP) | 1987-08-05 | — | — | EP | disclosed |