Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 12/20 | 0.48 |
| ▸ | ADRB1 | P08588 | 9/20 | 0.48 |
| ▸ | ADRB2 | P07550 | 6/20 | 0.48 |
| ▸ | SLC2A1 | P11166 | 3/20 | 0.47 |
| ▸ | CYP51A1 | Q16850 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9813880 | 1.00 | ADRB3 (0.48) | ADRB3ADRB1ADRB2SLC2A1CYP51A1 | |
| SCHEMBL9813877 | 1.00 | ADRB3 (0.48) | ADRB3ADRB1ADRB2SLC2A1CYP51A1 | |
| SCHEMBL10506511 | 0.91 | CYP51A1 (0.44) | ADRB3ADRB1ADRB2SLC2A1CYP51A1 | |
| SCHEMBL10506492 | 0.91 | CYP51A1 (0.44) | ADRB3ADRB1ADRB2SLC2A1CYP51A1 | |
| SCHEMBL9813906 | 0.89 | ADRB3 (0.45) | ADRB3ADRB1ADRB2SLC2A1MEN1 | |
| SCHEMBL9813917 | 0.89 | ADRB3 (0.45) | ADRB3ADRB1ADRB2SLC2A1MEN1 | |
| SCHEMBL9813911 | 0.89 | ADRB3 (0.45) | ADRB3ADRB1ADRB2SLC2A1MEN1 | |
| SCHEMBL10339991 | 0.88 | ADRB3 (0.57) | ADRB3ADRB1ADRB2SLC2A1MEN1 | |
| SCHEMBL10339992 | 0.88 | ADRB3 (0.57) | ADRB3ADRB1ADRB2SLC2A1MEN1 | |
| SCHEMBL9813959 | 0.88 | MEN1 (0.43) | ADRB3CYP51A1MEN1KMT2ACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5017619-A | Anitdiabetic | HOFFMANN-LA ROCHE INC. (US) | 1991-05-21 | — | — | US | claimed |
| EP-0198412-B1 | PHENETHANOL AMINE DERIVATIVES | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1989-03-22 | — | — | EP | claimed |
| US-5017619-A | Anitdiabetic | HOFFMANN-LA ROCHE INC. (US) | 1991-05-21 | — | — | US | disclosed |