Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 1/20 | 0.49 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.47 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.47 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.47 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.47 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23588163 | 0.98 | AOC3 (0.50) | AOC3S1PR2S1PR1S1PR3LPAR2 | |
| SCHEMBL11621719 | 0.93 | AOC3 (0.46) | AOC3S1PR2S1PR1S1PR3LPAR2 | |
| SCHEMBL6683963 | 0.92 | AOC3 (0.52) | AOC3S1PR2S1PR1S1PR3LPAR2 | |
| SCHEMBL24174177 | 0.92 | AOC3 (0.52) | AOC3S1PR2S1PR1S1PR3LPAR2 | |
| SCHEMBL4839687 | 0.87 | AOC3 (0.47) | AOC3SLC6A4SLC6A2SLC6A3GAA | |
| SCHEMBL13232162 | 0.86 | S1PR2 (0.48) | S1PR2S1PR1S1PR3LPAR2PTGER2 | |
| SCHEMBL9772644 | 0.86 | AOC3 (0.53) | AOC3SLC6A4SLC6A2SLC6A3GAA | |
| SCHEMBL6690160 | 0.86 | AOC3 (0.53) | AOC3SLC6A4SLC6A2SLC6A3GAA | |
| SCHEMBL9772894 | 0.86 | AOC3 (0.53) | AOC3SLC6A4SLC6A2SLC6A3GAA | |
| SCHEMBL13232166 | 0.84 | S1PR2 (0.46) | S1PR2S1PR1S1PR3LPAR2PTGER2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105218356-B | PPAR gamma selective regulator and preparation method and application thereof | 中国科学院上海药物研究所 | 2020-01-21 | — | — | CN | disclosed |
| CN-105218356-A | PPAR gamma selective adjusting control agent and its production and use | SHANGHAI INST MATERIA MEDICA | 2016-01-06 | — | — | CN | disclosed |
| EP-0314003-B1 | PROCESS FOR THE PREPARATION OF 1-ARYL ALKENES-1 | BASF Aktiengesellschaft (DE) | 1991-08-21 | — | — | EP | disclosed |
| US-4929786-A | DEHYDRATION, ARYLPHOSPHITE CATALYSTS | BASF AKTIENGESELLSCHAFT (DE) | 1990-05-29 | — | — | US | disclosed |
| EP-0314003-A2 | Process for the preparation of 1-aryl alkenes-1 | BASF Aktiengesellschaft (DE) | 1989-05-03 | — | — | EP | disclosed |