Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.49 |
| ▸ | EGFR | P00533 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | EEF2K | O00418 | 1/20 | 0.43 |
| ▸ | SRC | P12931 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9814731 | 1.00 | CYP1A2 (0.54) | CYP1A2CYP2C9ALOX5PTGS1PTGS2 | |
| SCHEMBL9814829 | 0.95 | CYP1A2 (0.52) | CYP1A2CYP2C9ALOX5PTGS1PTGS2 | |
| SCHEMBL9814826 | 0.95 | CYP1A2 (0.52) | CYP1A2CYP2C9ALOX5PTGS1PTGS2 | |
| SCHEMBL9814684 | 0.88 | CYP1A2 (0.57) | CYP1A2CYP2C9ALOX5PTGS1PTGS2 | |
| SCHEMBL9814683 | 0.88 | CYP1A2 (0.57) | CYP1A2CYP2C9ALOX5PTGS1PTGS2 | |
| SCHEMBL9814650 | 0.88 | CYP1A2 (0.59) | CYP1A2CYP2C9ALOX5PTGS1PTGS2 | |
| SCHEMBL9814646 | 0.88 | CYP1A2 (0.59) | CYP1A2CYP2C9ALOX5PTGS1PTGS2 | |
| SCHEMBL9814809 | 0.85 | CYP1A2 (0.51) | CYP1A2CYP2C9ALOX5PTGS1PTGS2 | |
| SCHEMBL9814810 | 0.85 | CYP1A2 (0.51) | CYP1A2CYP2C9ALOX5PTGS1PTGS2 | |
| SCHEMBL14479539 | 0.85 | CYP1A2 (0.59) | CYP1A2CYP2C9ALOX5PTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0204964-B1 | 2-PYRROLIDONE DERIVATIVES, PROCESS FOR PREPARING THEM, PHARMACEUTICAL COMPOSITION AND USE | Eisai Co., Ltd. (JP) | 1991-08-28 | — | — | EP | disclosed |
| US-4833160-A | ANTIINFLAMMATORY AGENTS, ANALGESICS | EISAI CO., LTD. (JP) | 1989-05-23 | — | — | US | disclosed |
| EP-0204964-A1 | 2-Pyrrolidone derivatives, process for preparing them, pharmaceutical composition and use | Eisai Co., Ltd. (JP) | 1986-12-17 | — | — | EP | disclosed |