Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A1 | P43005 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 4/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.41 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | ANPEP | P15144 | 1/20 | 0.33 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16388417 | 0.87 | TSHR (0.55) | SLC1A1TSHRHSD17B10CA1CA2 | |
| SCHEMBL526220 | 0.82 | SLC1A1 (0.49) | SLC1A1TSHRHSD17B10CA1CA2 | |
| SCHEMBL9509840 | 0.82 | CA1 (0.62) | SLC1A1TSHRHSD17B10CA1CA2 | |
| SCHEMBL2871738 | 0.81 | CA1 (0.45) | TSHRHSD17B10CA1CA2FOLH1 | |
| SCHEMBL2879991 | 0.80 | — | — | |
| SCHEMBL579709 | 0.80 | CA1 (0.50) | SLC1A1TSHRCA1CA2KMT2A | |
| SCHEMBL18264428 | 0.80 | TSHR (0.52) | SLC1A1TSHRCA1CA2FOLH1 | |
| SCHEMBL20464696 | 0.80 | SLC1A1 (0.47) | SLC1A1TSHRHSD17B10CA1CA2 | |
| SCHEMBL8107918 | 0.80 | TSHR (0.54) | SLC1A1TSHRHSD17B10CA1CA2 | |
| SCHEMBL17165780 | 0.80 | SLC1A1 (0.47) | SLC1A1TSHRHSD17B10CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4927966-A | ANTITUMOR | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 1990-05-22 | — | — | US | claimed |
| US-5010103-A | Anticarcinogenic agents | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF N.Y. (US) | 1991-04-23 | — | — | US | disclosed |
| US-4927966-A | ANTITUMOR | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 1990-05-22 | — | — | US | disclosed |