Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 4/20 | 0.49 |
| ▸ | PPARA | Q07869 | 3/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
| ▸ | CNR1 | P21554 | 3/20 | 0.37 |
| ▸ | CNR2 | P34972 | 2/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | LDHA | P00338 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5668779 | 0.84 | ACACB (0.50) | ACACBPPARAPPARGSLC6A4 | |
| SCHEMBL7107803 | 0.84 | ACACB (0.47) | ACACBPPARAPPARGSLC6A4CNR1 | |
| SCHEMBL2030935 | 0.82 | ACACB (0.46) | ACACBPPARAPPARGSLC6A4SLC6A2 | |
| SCHEMBL6272156 | 0.81 | ACACB (0.50) | ACACBSLC6A4SLC6A2SLC6A3 | |
| SCHEMBL7976221 | 0.79 | SLC6A4 (0.60) | ACACBSLC6A4LDHA | |
| SCHEMBL8283102 | 0.79 | SLC6A4 (0.60) | ACACBSLC6A4LDHA | |
| SCHEMBL19015929 | 0.78 | SLC6A4 (0.63) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL319906 | 0.77 | PPARA (0.63) | ACACBPPARAPPARGSLC6A4SLC6A2 | |
| SCHEMBL12040135 | 0.76 | ACACB (0.53) | ACACBPPARAPPARGCNR1CNR2 | |
| SCHEMBL16743914 | 0.76 | ACACB (0.57) | ACACBPPARAPPARGCNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0447947-A1 | N-(3-Phenyl-2-methylpropyl and -methyl-prop-2-enyl)-azaheterocycles | BASF Aktiengesellschaft (DE) | 1991-09-25 | — | — | EP | disclosed |