Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | PARP1 | P09874 | 4/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.45 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.45 |
| ▸ | GLS | O94925 | 1/20 | 0.45 |
| ▸ | GLS2 | Q9UI32 | 1/20 | 0.45 |
| ▸ | PIM1 | P11309 | 5/20 | 0.44 |
| ▸ | PIM3 | Q86V86 | 5/20 | 0.44 |
| ▸ | PIM2 | Q9P1W9 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | STK17B | O94768 | 2/20 | 0.44 |
| ▸ | BCL2 | P10415 | 2/20 | 0.44 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.44 |
| ▸ | CDK7 | P50613 | 2/20 | 0.44 |
| ▸ | DAPK1 | P53355 | 2/20 | 0.44 |
| ▸ | CAMK4 | Q16566 | 2/20 | 0.44 |
| ▸ | MAPK15 | Q8TD08 | 2/20 | 0.44 |
| ▸ | PNPLA2 | Q96AD5 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL98151 | 1.00 | PTPN1 (0.48) | PTPN1HPGDPARP1PPARANR1H4 | |
| SCHEMBL97652 | 0.81 | HPGD (0.53) | PTPN1HPGDGLSGLS2PIM1 | |
| SCHEMBL97651 | 0.81 | HPGD (0.53) | PTPN1HPGDGLSGLS2PIM1 | |
| SCHEMBL98322 | 0.75 | NAT1 (0.49) | PTPN1HPGDPIM1PIM3PIM2 | |
| SCHEMBL98320 | 0.75 | NAT1 (0.49) | PTPN1HPGDPIM1PIM3PIM2 | |
| SCHEMBL97198 | 0.74 | PIK3CG (0.52) | PIM1 | |
| SCHEMBL97199 | 0.74 | PIK3CG (0.52) | PIM1 | |
| SCHEMBL97492 | 0.71 | FFAR1 (0.44) | PPARAALDH1A1POLB | |
| SCHEMBL97235 | 0.70 | PARP1 (0.58) | PTPN1HPGDPARP1PPARANR1H4 | |
| SCHEMBL97234 | 0.70 | PARP1 (0.58) | PTPN1HPGDPARP1PPARANR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8362252-B2 | Carbostyril compound | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2013-01-29 | — | — | US | disclosed |
| EP-2426128-A1 | Carbostyril compound | Otsuka Pharmaceutical Co., Limited (JP) | 2012-03-07 | — | — | EP | disclosed |
| US-20100261705-A1 | CARBOSTYRIL COMPOUND | OTSUKA PHARMACEUTICAL CO., LTD. | 2010-10-14 | — | — | US | disclosed |
| US-7777038-B2 | Carbostyril compound | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2010-08-17 | — | — | US | disclosed |
| US-20070179173-A1 | Carbostyril compound | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2007-08-02 | — | — | US | disclosed |
| EP-1797082-A1 | CARBOSTYRIL COMPOUND | Otsuka Pharmaceutical Company, Limited (JP) | 2007-06-20 | — | — | EP | disclosed |
| WO-2006035954-A1 | CARBOSTYRIL COMPOUND | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-04-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070179173-A1 | Carbostyril compound | GTF2F1, F3, GTF2F2 | PTPN1 1691/4885HPGD 2322/4885PARP1 3173/4885 |
| US-20100261705-A1 | CARBOSTYRIL COMPOUND | GTF2F1, F3, GTF2F2 | PTPN1 1691/4885HPGD 2322/4885PARP1 3173/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.