Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | NOS3 | P29474 | 2/20 | 0.53 |
| ▸ | NOS2 | P35228 | 1/20 | 0.53 |
| ▸ | MAOA | P21397 | 2/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 2/20 | 0.34 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.34 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.34 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3452241 | 0.98 | KDM4E (0.57) | ALDH1A1KDM4ENOS3NOS2MAOA | |
| SCHEMBL7509399 | 0.82 | KDM4E (0.60) | ALDH1A1KDM4ENOS3NOS2MAOA | |
| SCHEMBL29361631 | 0.82 | KDM4E (0.60) | ALDH1A1KDM4ENOS3NOS2MAOA | |
| SCHEMBL22995932 | 0.81 | KDM4E (0.63) | ALDH1A1KDM4ENOS3NOS2MAOA | |
| SCHEMBL7819962 | 0.81 | KDM4E (0.58) | ALDH1A1KDM4ENOS3NOS2MAOA | |
| SCHEMBL30952113 | 0.81 | KDM4E (0.63) | ALDH1A1KDM4ENOS3NOS2MAOA | |
| SCHEMBL10881436 | 0.78 | KDM4E (0.55) | ALDH1A1KDM4ENOS3NOS2MAOA | |
| SCHEMBL29757769 | 0.78 | KDM4E (0.55) | ALDH1A1KDM4ENOS3NOS2MAOA | |
| SCHEMBL9095677 | 0.78 | KDM4E (0.55) | ALDH1A1KDM4ENOS3NOS2MAOA | |
| SCHEMBL5009247 | 0.78 | KDM4E (0.55) | ALDH1A1KDM4ENOS3NOS2MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102093346-B | Preparation method of praziquantel | ZHEJIANG GENEBEST PHARMACEUTICAL CO LTD | 2012-09-05 | — | — | CN | claimed |
| CN-102093346-A | Preparation method of praziquantel | ZHEJIANG GENEBEST PHARMACEUTICAL CO LTD | 2011-06-15 | — | — | CN | claimed |
| CN-102093346-B | Preparation method of praziquantel | ZHEJIANG GENEBEST PHARMACEUTICAL CO LTD | 2012-09-05 | — | — | CN | disclosed |
| CN-102093346-A | Preparation method of praziquantel | ZHEJIANG GENEBEST PHARMACEUTICAL CO LTD | 2011-06-15 | — | — | CN | disclosed |
| EP-0232989-B1 | ISOQUINOLINE DERIVATIVES | Dr. Lo. Zambeletti S.p.A. (IT) | 1991-08-21 | — | — | EP | disclosed |
| US-4806547-A | Isoquinoline derivatives, analgesic compounds thereof and method of treating pain | DR. LO. ZAMBELETTI SPA (IT) | 1989-02-21 | — | — | US | disclosed |
| EP-0232989-A2 | Isoquinoline derivatives | Dr. Lo. Zambeletti S.p.A. (IT) | 1987-08-19 | — | — | EP | disclosed |