SCHEMBL9815670

SCHEMBL9815670

CCCCCC1CCC(COc2cc[c]cc2)CC1

nearest known ligand 0.40

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
PARP15 Q460N3 1/20 0.39
PARP10 Q53GL7 1/20 0.39
PARP2 Q9UGN5 1/20 0.39
TDP1 Q9NUW8 1/20 0.38
SIGMAR1 Q99720 1/20 0.38
RIPK1 Q13546 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9815672 1.00 PARP15 (0.39) PARP15PARP10PARP2TDP1SIGMAR1
SCHEMBL10827074 0.98 PARP15 (0.38) PARP15PARP10PARP2TDP1SIGMAR1
SCHEMBL10827078 0.98 PARP15 (0.38) PARP15PARP10PARP2TDP1SIGMAR1
SCHEMBL9815661 0.89 PARP15 (0.41) PARP15PARP10PARP2TDP1SIGMAR1
SCHEMBL9815659 0.89 PARP15 (0.41) PARP15PARP10PARP2TDP1SIGMAR1
SCHEMBL9346047 0.84 NR5A1 (0.45) PARP15PARP10PARP2TDP1
SCHEMBL751432 0.83 PARP15 (0.50) PARP15PARP10PARP2TDP1SIGMAR1
SCHEMBL9345672 0.83 NR5A1 (0.47) PARP15PARP10PARP2TDP1
SCHEMBL9346256 0.83 NR5A1 (0.47) PARP15PARP10PARP2TDP1
SCHEMBL9344226 0.83 NR5A1 (0.47) PARP15PARP10PARP2TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0120463-B1 ANTHRAQUINONE DYES AND LIQUID CRYSTAL COMPOSITIONS INCLUDING THE SAME HITACHI, LTD. (JP) 1991-11-06 EP disclosed
US-5032312-A Liquid crystals HOFFMANN-LA ROCHE INC. (US) 1991-07-16 US disclosed
US-4610804-A Anthraquinone dyes and liquid crystal compositions including the same HITACHI, LTD. (JP) 1986-09-09 US disclosed
US-4528113-A Anthraquinone dye and liquid crystal composition containing the dye MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) 1985-07-09 US disclosed
EP-0120717-A2 Anthraquinone dyes and liquid crystal compositions containing the dyes MITSUBISHI KASEI CORPORATION (JP) 1984-10-03 EP disclosed
EP-0120463-A2 Anthraquinone dyes and liquid crystal compositions including the same HITACHI, LTD. (JP) 1984-10-03 EP disclosed