Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9425420 | 0.91 | ABCB1 (0.47) | ABCB1 | |
| SCHEMBL9815897 | 0.83 | POLB (0.51) | ABCB1 | |
| SCHEMBL9425384 | 0.83 | ABCB1 (0.45) | ABCB1 | |
| SCHEMBL10718620 | 0.81 | ABCB1 (0.59) | ABCB1 | |
| SCHEMBL9815850 | 0.81 | ABCB1 (0.50) | ABCB1 | |
| SCHEMBL9815831 | 0.79 | ABCB1 (0.49) | ABCB1 | |
| SCHEMBL9425891 | 0.79 | ABCB1 (0.57) | ABCB1 | |
| SCHEMBL9425780 | 0.78 | ABCB1 (0.50) | ABCB1 | |
| SCHEMBL10748923 | 0.77 | POLB (0.67) | — | |
| SCHEMBL10719141 | 0.76 | ABCB1 (0.57) | ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0253468-B1 | SIX-MEMBERED HETEROCYCLIC DERIVATIVES OF N'SUBSTITUTED-N,N'-DIACYLHYDRAZINES | ROHM AND HAAS COMPANY (US) | 1991-11-06 | — | — | EP | disclosed |