Ethylene

Ethylene

SCHEMBL9815947

C=C.COc1ccc2ccccc2c1

nearest known ligand 0.91

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.91
CYP2A6 P11509 1/20 0.91
RAB9A P51151 4/20 0.55
NQO2 P16083 3/20 0.55
LMNA P02545 2/20 0.55
SMN1; SMN2 Q16637 2/20 0.55
L3MBTL1 Q9Y468 2/20 0.55
HTT P42858 1/20 0.55
TDP1 Q9NUW8 1/20 0.55
PPARG P37231 1/20 0.53
NPC1 O15118 3/20 0.52
MEN1 O00255 2/20 0.52
KMT2A Q03164 2/20 0.52
KDM4E B2RXH2 2/20 0.52
HSD17B1 P14061 1/20 0.52
HSD17B2 P37059 1/20 0.52
ALDH1A1 P00352 1/20 0.52
POLB P06746 1/20 0.52
ACHE P22303 2/20 0.50
ALOX5 P09917 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL112792 0.95 CYP1A2 (1.00) CYP1A2CYP2A6RAB9ANQO2LMNA
SCHEMBL29353188 0.95 CYP1A2 (1.00) CYP1A2CYP2A6RAB9ANQO2LMNA
SCHEMBL5311432 0.95 CYP1A2 (1.00) CYP1A2CYP2A6RAB9ANQO2LMNA
Formaldehyde SCHEMBL27438517 0.93 CYP2A6 (0.86) CYP1A2CYP2A6RAB9ANQO2LMNA
Methane SCHEMBL9286464 0.93 CYP1A2 (0.95) CYP1A2CYP2A6RAB9ANQO2LMNA
Ethane SCHEMBL28740950 0.93 CYP1A2 (0.95) CYP1A2CYP2A6RAB9ANQO2LMNA
SCHEMBL27498364 0.93 CYP1A2 (0.95) CYP1A2CYP2A6RAB9ANQO2LMNA
Water SCHEMBL17079094 0.93 CYP1A2 (0.95) CYP1A2CYP2A6RAB9ANQO2LMNA
SCHEMBL11884025 0.93 CYP1A2 (0.95) CYP1A2CYP2A6RAB9ANQO2LMNA
Naphthalene SCHEMBL18344242 0.93 CYP1A2 (0.95) CYP1A2CYP2A6RAB9ANQO2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117800821-A Method and catalyst for preparing chiral alpha-aryl propanal through asymmetric hydroformylation 青岛科技大学 2024-04-02 CN disclosed
CN-107141391-B Ethylene-polar styrene quasi-random copolymer and preparation method thereof 中国科学院长春应用化学研究所 2020-03-13 CN disclosed
CN-107141391-A A kind of quasi- random copolymer of ethylene polar styrene and preparation method thereof 中国科学院长春应用化学研究所 2017-09-08 CN disclosed
CN-1212254-A Method for preparing naproxen of methyl ester and S-(+) naproxen of methyl ester by using carbonylation LANZHOU CHEM PHYS INST (CN) 1999-03-31 CN disclosed
EP-0444171-A1 ASYMMETRIC SYNTHESIS OF ACIDS BY THE PALLADIUM CATALYSED HYDROCARBOXYLATION OF OLEFINS Université d'Ottawa/University of Ottawa (CA) 1991-09-04 EP disclosed
WO-1991003452-A1 ASYMMETRIC SYNTHESIS OF ACIDS BY THE PALLADIUM CATALYSED HYDROCARBOXYLATION OF OLEFINS THE BRITISH PETROLEUM COMPANY PLC (GB) 1991-03-21 WO disclosed