⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyridine SCHEMBL28209678 | 0.83 | TSHR (0.38) | — | |
| SCHEMBL27747352 | 0.79 | — | — | |
| SCHEMBL5662539 | 0.75 | — | — | |
| SCHEMBL28293382 | 0.74 | — | — | |
| SCHEMBL156217 | 0.72 | — | — | |
| SCHEMBL1162272 | 0.72 | — | — | |
| SCHEMBL2270853 | 0.72 | — | — | |
| SCHEMBL2005072 | 0.72 | — | — | |
| Hydrochloric Acid SCHEMBL7241248 | 0.70 | — | — | |
| SCHEMBL357316 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119351388-A | Application of porous carrier material in microorganism immobilization | 南京大学 | 2025-01-24 | — | — | CN | disclosed |
| CN-114539241-B | Pleuromutilin derivative containing thiazole-pyridine methyl aromatic heterocyclic quaternary ammonium salt side chain and preparation method and application thereof | 西咸新区沣厚原创医药科技有限公司 | 2024-06-04 | — | — | CN | disclosed |
| CN-114456160-B | Oxadiazole-pyridine quaternary ammonium salt side chain-containing pleuromutilin derivative with drug-resistant bacteria resisting activity, and preparation method and application thereof | 西安康远晟生物医药科技有限公司 | 2024-02-23 | — | — | CN | disclosed |
| CN-114539241-A | Pleuromutilin derivative containing thiazole-picolyl aromatic heterocyclic quaternary ammonium salt side chain and preparation method and application thereof | 陕西科技大学 | 2022-05-27 | — | — | CN | disclosed |
| CN-114456160-A | Oxadiazole-pyridine quaternary ammonium salt side chain containing pleuromutilin derivative with drug-resistant bacterium resisting activity and preparation method and application thereof | 西安康远晟生物医药科技有限公司 | 2022-05-10 | — | — | CN | disclosed |
| CN-104428293-B | Adjust the benzimidazole of TNF α | UCB生物制药私人有限公司 | 2018-06-08 | — | — | CN | disclosed |
| CN-107252429-A | New antiinflammatory | 雷斯韦洛吉克斯公司 | 2017-10-17 | — | — | CN | disclosed |
| CN-102458405-B | Novel anti-inflammatory agents | 雷斯韦洛吉克斯公司 | 2017-06-23 | — | — | CN | disclosed |
| CN-106536515-A | Compounds useful as immunomodulators | 百时美施贵宝公司 | 2017-03-22 | — | — | CN | disclosed |
| US-9249154-B2 | Compounds and therapeutic use thereof for protein kinase inhibition | WU ZHANGGUI (US) | 2016-02-02 | — | — | US | disclosed |
| US-20110009415-A1 | Thienopyridazine Compounds, Their Preparations, Pharmaceutical Compositions And Uses | WU, ZHANGGUI (CN) | 2011-01-13 | — | — | US | disclosed |
| US-20110009415-A1 | Thienopyridazine Compounds, Their Preparations, Pharmaceutical Compositions And Uses | WU, ZHANGGUI (CN) | 2011-01-13 | — | — | US | disclosed |
| US-20110009415-A1 | Thienopyridazine Compounds, Their Preparations, Pharmaceutical Compositions And Uses | WU, ZHANGGUI (CN) | 2011-01-13 | — | — | US | disclosed |
| EP-2241569-A1 | THIENOPYRIDAZINE COMPOUNDS, THEIR PREPARATIONS, PHARMACEUTICAL COMPOSITIONS AND USES | Zhejiang Medicine Co., Ltd. Xinchang Pharmaceutical Factory (CN) | 2010-10-20 | — | — | EP | disclosed |
| EP-2241569-A1 | THIENOPYRIDAZINE COMPOUNDS, THEIR PREPARATIONS, PHARMACEUTICAL COMPOSITIONS AND USES | Zhejiang Medicine Co., Ltd. Xinchang Pharmaceutical Factory (CN) | 2010-10-20 | — | — | EP | disclosed |
| US-20090275585-A1 | Novel Compounds and Therapeutic Use Thereof for Protein Kinase Inhibition | WU ZHANGGUI | 2009-11-05 | — | — | US | disclosed |
| US-20090275585-A1 | Novel Compounds and Therapeutic Use Thereof for Protein Kinase Inhibition | WU ZHANGGUI | 2009-11-05 | — | — | US | disclosed |
| US-20090275585-A1 | Novel Compounds and Therapeutic Use Thereof for Protein Kinase Inhibition | WU ZHANGGUI | 2009-11-05 | — | — | US | disclosed |
| US-4440779-A | Tricyclic derivatives of substituted pyrrole acids as analgesic and anti-inflammatory agents | MERCK & CO., INC. (US) | 1984-04-03 | — | — | US | disclosed |
| EP-0068460-A1 | Tricyclic derivatives of substituted pyrrole acids as analgesic and anti-inflammatory agents | MERCK & CO. INC. (US) | 1983-01-05 | — | — | EP | disclosed |