SCHEMBL9816864

SCHEMBL9816864

CCN(Cc1ccccc1)[C@@H](C)CCl

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCHE P06276 2/20 0.51
TSHR P16473 6/20 0.49
ALDH1A1 P00352 4/20 0.49
ADRA2B P18089 3/20 0.49
HTR2A P28223 3/20 0.49
KCNH2 Q12809 3/20 0.49
SMN1; SMN2 Q16637 2/20 0.49
ADRA2C P18825 2/20 0.49
SLC6A2 P23975 2/20 0.49
ADRA1A P35348 2/20 0.49
SLC6A3 Q01959 2/20 0.49
ADRA2A P08913 2/20 0.49
HRH1 P35367 2/20 0.49
SLC22A2 O15244 1/20 0.49
SLC22A1 O15245 1/20 0.49
SLC22A3 O75751 1/20 0.49
ESR1 P03372 1/20 0.49
CHRM2 P08172 1/20 0.49
HTR1A P08908 1/20 0.49
ADORA3 P0DMS8 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9816888 1.00 BCHE (0.51) BCHETSHRALDH1A1ADRA2BHTR2A
Hydrochloric Acid SCHEMBL9816861 0.98 TSHR (0.50) BCHETSHRALDH1A1ADRA2BHTR2A
Hydrochloric Acid SCHEMBL9816855 0.98 TSHR (0.50) BCHETSHRALDH1A1ADRA2BHTR2A
SCHEMBL12126080 0.85 BCHE (0.54) BCHETSHRALDH1A1ADRA2BHTR2A
SCHEMBL19046875 0.81 BCHE (0.51) BCHETSHRALDH1A1ADRA2BHTR2A
SCHEMBL12126093 0.81 BCHE (0.58) BCHETSHRALDH1A1ADRA2BHTR2A
SCHEMBL19472433 0.81 BCHE (0.51) BCHETSHRALDH1A1ADRA2BHTR2A
SCHEMBL9816880 0.81 BCHE (0.51) BCHETSHRALDH1A1ADRA2BHTR2A
SCHEMBL21431254 0.81 BCHE (0.58) BCHETSHRALDH1A1ADRA2BHTR2A
SCHEMBL12124992 0.81 BCHE (0.58) BCHETSHRALDH1A1ADRA2BHTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0301925-B1 PROCESS FOR THE ENANTIOSPECIFIC PREPARATION OF (S)2-ETHYL AMINO-1-3-(TRIFLUOROMETHYL PHENYL) PROPANE ADIR ET COMPAGNIE (FR) 1991-10-23 EP claimed
EP-0301925-A1 Process for the enantiospecific preparation of (S)2-ethyl amino-1-3-(trifluoromethyl phenyl) propane ADIR ET COMPAGNIE (FR) 1989-02-01 EP disclosed