Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 4/20 | 0.56 |
| ▸ | HTR2B | P41595 | 3/20 | 0.56 |
| ▸ | HTR2C | P28335 | 2/20 | 0.56 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.53 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.53 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | DRD3 | P35462 | 2/20 | 0.53 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | CETP | P11597 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9816878 | 1.00 | HTR2A (0.56) | HTR2AHTR2BHTR2CSLC6A4SIGMAR1 | |
| SCHEMBL2738920 | 0.90 | HTR2A (0.64) | HTR2AHTR2BHTR2CSLC6A4SIGMAR1 | |
| SCHEMBL9155414 | 0.86 | HTR2A (0.52) | HTR2AHTR2BHTR2CSLC6A4SIGMAR1 | |
| SCHEMBL9472455 | 0.86 | MEN1 (0.62) | HTR2AHTR2BHTR2CSLC6A4SIGMAR1 | |
| SCHEMBL9472615 | 0.86 | HTR2A (0.52) | HTR2AHTR2BHTR2CSLC6A4SIGMAR1 | |
| SCHEMBL9155234 | 0.86 | MEN1 (0.62) | HTR2AHTR2BHTR2CSLC6A4SIGMAR1 | |
| SCHEMBL9472697 | 0.85 | HTR2A (0.51) | HTR2AHTR2BHTR2CSLC6A4SIGMAR1 | |
| Hydrochloric Acid SCHEMBL9472549 | 0.85 | CYP3A4 (0.52) | HTR2AHTR2BHTR2CSLC6A4SIGMAR1 | |
| SCHEMBL9162302 | 0.85 | HTR2A (0.51) | HTR2AHTR2BHTR2CSLC6A4SIGMAR1 | |
| Hydrochloric Acid SCHEMBL9472496 | 0.85 | MEN1 (0.61) | HTR2AHTR2BHTR2CSLC6A4SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0301925-B1 | PROCESS FOR THE ENANTIOSPECIFIC PREPARATION OF (S)2-ETHYL AMINO-1-3-(TRIFLUOROMETHYL PHENYL) PROPANE | ADIR ET COMPAGNIE (FR) | 1991-10-23 | — | — | EP | claimed |
| EP-0301925-A1 | Process for the enantiospecific preparation of (S)2-ethyl amino-1-3-(trifluoromethyl phenyl) propane | ADIR ET COMPAGNIE (FR) | 1989-02-01 | — | — | EP | disclosed |