Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 3/20 | 0.33 |
| ▸ | CES1 | P23141 | 3/20 | 0.33 |
| ▸ | LSS | P48449 | 1/20 | 0.32 |
| ▸ | DNM1 | Q05193 | 5/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3653854 | 1.00 | TSHR (0.40) | TSHRTHRBCES2CES1LSS | |
| SCHEMBL23001233 | 1.00 | TSHR (0.40) | TSHRTHRBCES2CES1LSS | |
| SCHEMBL11765195 | 0.98 | TSHR (0.38) | TSHRTHRBCES2CES1LSS | |
| SCHEMBL5668985 | 0.97 | — | — | |
| SCHEMBL296474 | 0.84 | TSHR (0.50) | TSHRTHRBCES2CES1DNM1 | |
| SCHEMBL4791112 | 0.84 | TSHR (0.50) | TSHRTHRBCES2CES1DNM1 | |
| SCHEMBL9818219 | 0.84 | TSHR (0.50) | TSHRTHRBCES2CES1DNM1 | |
| SCHEMBL3160216 | 0.84 | TSHR (0.50) | TSHRTHRBCES2CES1DNM1 | |
| SCHEMBL3025854 | 0.84 | TSHR (0.50) | TSHRTHRBCES2CES1DNM1 | |
| SCHEMBL14478066 | 0.84 | TSHR (0.50) | TSHRTHRBCES2CES1DNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0213944-B1 | NOVEL CELLULOSE DERIVATIVE, PROCESS FOR PREPARING THE SAME AND SULFUR DIOXIDE GAS PERMSELECTIVE MEMBRANE COMPRISING THE SAME | Shin-Etsu Chemical Co., Ltd. (JP) | 1991-10-23 | — | — | EP | disclosed |
| EP-0160508-B1 | PHENOL DERIVATIVES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1989-05-31 | — | — | EP | disclosed |
| US-4760061-A | Antioestrogenic agent | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-07-26 | — | — | US | disclosed |
| US-4694077-A | A HYDROCARBYLSULFINYL ETHYL CELLULOSE BY REACTING A HYDROCARBYL VINYL SULFOXIDE AND A CELLULOSE; FILMS; CASTINGS | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1987-09-15 | — | — | US | disclosed |
| EP-0213944-A2 | Novel cellulose derivative, process for preparing the same and sulfur dioxide gas permselective membrane comprising the same | Shin-Etsu Chemical Co., Ltd. (JP) | 1987-03-11 | — | — | EP | disclosed |
| EP-0160508-A2 | Phenol derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1985-11-06 | — | — | EP | disclosed |