SCHEMBL9816985

SCHEMBL9816985

CCCC(c1ccc(O)c(-c2ccccc2)c1)(c1ccc(O)c(-c2ccccc2)c1)c1cccc(C)c1C

nearest known ligand 0.41

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 13/20 0.41
ESR2 Q92731 5/20 0.41
AR P10275 2/20 0.41
CNR1 P21554 3/20 0.40
CNR2 P34972 3/20 0.40
BACE1 P56817 2/20 0.36
TRPA1 O75762 1/20 0.35
ATM Q13315 1/20 0.35
HSD17B1 P14061 1/20 0.34
HSD17B2 P37059 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9817021 0.93 CNR1 (0.44) ESR1ESR2ARCNR1CNR2
SCHEMBL9816999 0.92 CNR1 (0.48) ESR1ESR2ARCNR1CNR2
SCHEMBL9817105 0.91 ESR1 (0.44) ESR1ESR2ARCNR1CNR2
SCHEMBL9817004 0.90 ESR1 (0.39) ESR1ESR2ARCNR1CNR2
SCHEMBL9817047 0.84 ESR1 (0.47) ESR1ESR2ARCNR1CNR2
SCHEMBL9817058 0.83 CNR1 (0.44) ESR1ESR2ARCNR1CNR2
SCHEMBL9816986 0.83 ESR1 (0.41) ESR1ESR2ARCNR1CNR2
SCHEMBL9817054 0.82 BACE1 (0.42) ESR1ESR2CNR1CNR2BACE1
SCHEMBL2867989 0.82 BACE1 (0.44) ESR1ESR2ARCNR1CNR2
SCHEMBL9816988 0.81 ESR1 (0.41) ESR1ESR2ARCNR1CNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0277627-B1 POLYFORMAL RESINS AND PROCESS FOR PRODUCING SAID RESINS IDEMITSU KOSAN COMPANY LIMITED (JP) 1991-10-23 EP disclosed
US-4801679-A Polyformal resin and process for producing said resin IDEMITSU KOSAN CO., LTD. (JP) 1989-01-31 US disclosed
EP-0277627-A1 Polyformal resins and process for producing said resins IDEMITSU KOSAN COMPANY LIMITED (JP) 1988-08-10 EP disclosed