SCHEMBL9817038

SCHEMBL9817038

Oc1ccc(C2(c3ccc(O)c(-c4ccccc4)c3)CCCCCCCCC2)cc1-c1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 4/20 0.56
ESR2 Q92731 4/20 0.56
BACE1 P56817 2/20 0.48
ALDH1A1 P00352 3/20 0.43
HPGD P15428 1/20 0.42
BCL2L1 Q07817 1/20 0.42
HSD17B10 Q99714 1/20 0.42
PELI1 Q96FA3 1/20 0.41
MAOA P21397 1/20 0.40
MAOB P27338 1/20 0.40
HSD17B1 P14061 1/20 0.40
HSD17B2 P37059 1/20 0.40
ACHE P22303 1/20 0.40
SLC6A2 P23975 1/20 0.39
SLC6A4 P31645 1/20 0.39
SLC6A3 Q01959 1/20 0.39
ALOX5 P09917 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
CYP2D6 P10635 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6294095 1.00 ESR1 (0.56) ESR1ESR2BACE1ALDH1A1HPGD
SCHEMBL9817120 1.00 ESR1 (0.56) ESR1ESR2BACE1ALDH1A1HPGD
SCHEMBL3303467 1.00 ESR1 (0.56) ESR1ESR2BACE1ALDH1A1HPGD
SCHEMBL9816983 1.00 ESR1 (0.56) ESR1ESR2BACE1ALDH1A1HPGD
SCHEMBL30443573 1.00 ESR1 (0.56) ESR1ESR2BACE1ALDH1A1HPGD
SCHEMBL29459479 1.00 ESR1 (0.56) ESR1ESR2BACE1ALDH1A1HPGD
SCHEMBL9817137 1.00 ESR1 (0.56) ESR1ESR2BACE1ALDH1A1HPGD
SCHEMBL29802337 1.00 ESR1 (0.56) ESR1ESR2BACE1ALDH1A1HPGD
SCHEMBL9816996 1.00 ESR1 (0.56) ESR1ESR2BACE1ALDH1A1HPGD
SCHEMBL297971 1.00 ESR1 (0.56) ESR1ESR2BACE1ALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0277627-B1 POLYFORMAL RESINS AND PROCESS FOR PRODUCING SAID RESINS IDEMITSU KOSAN COMPANY LIMITED (JP) 1991-10-23 EP disclosed
US-4801679-A Polyformal resin and process for producing said resin IDEMITSU KOSAN CO., LTD. (JP) 1989-01-31 US disclosed
EP-0277627-A1 Polyformal resins and process for producing said resins IDEMITSU KOSAN COMPANY LIMITED (JP) 1988-08-10 EP disclosed