Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | RARB | P10826 | 4/20 | 0.51 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.47 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.47 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.47 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.47 |
| ▸ | THRA | P10827 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | RARA | P10276 | 1/20 | 0.42 |
| ▸ | RARG | P13631 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10557115 | 0.90 | RARB (0.52) | MAPTRAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL10555207 | 0.90 | RARB (0.52) | MAPTRAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL9399114 | 0.90 | RARB (0.52) | MAPTRAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL10558978 | 0.90 | RARB (0.52) | MAPTRAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL10560121 | 0.90 | RARB (0.52) | MAPTRAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL10558236 | 0.90 | RARB (0.52) | MAPTRAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL10560165 | 0.90 | RARB (0.52) | MAPTRAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL10554428 | 0.90 | RARB (0.52) | MAPTRAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL10555705 | 0.90 | RARB (0.52) | MAPTRAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL10554229 | 0.90 | RARB (0.52) | MAPTRAB9ASMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5055221-A | Rapidly switching ferroelectric display element | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1991-10-08 | — | — | US | disclosed |
| EP-0227717-B1 | NITROGEN-CONTAINING HETEROCYCLIC ESTERS | MERCK PATENT GmbH (DE) | 1990-04-25 | — | — | EP | disclosed |
| EP-0224579-B1 | SMECTIC LIQUID CRYSTALLINE PHASES | MERCK PATENT GmbH (DE) | 1990-01-24 | — | — | EP | disclosed |
| US-4820839-A | LIQUID CRYSTALS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1989-04-11 | — | — | US | disclosed |
| EP-0227717-A1 | NITROGEN-CONTAINING HETEROCYCLIC ESTERS. | MERCK PATENT GMBH (DE) | 1987-07-08 | — | — | EP | disclosed |
| EP-0224579-A1 | SMECTIC LIQUID CRYSTALLINE PHASES. | MERCK PATENT GMBH (DE) | 1987-06-10 | — | — | EP | disclosed |
| WO-1986007055-A1 | NITROGEN-CONTAINING HETEROCYCLIC ESTERS | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1986-12-04 | — | — | WO | disclosed |
| WO-1986007085-A1 | SMECTIC LIQUID CRYSTALLINE PHASES | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1986-12-04 | — | — | WO | disclosed |