Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 2/20 | 0.67 |
| ▸ | MAPT | P10636 | 8/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.65 |
| ▸ | THRB | P10828 | 2/20 | 0.60 |
| ▸ | NPC1 | O15118 | 4/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 4/20 | 0.52 |
| ▸ | NFKB2 | Q00653 | 4/20 | 0.52 |
| ▸ | RELA | Q04206 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9817769 | 1.00 | RARB (0.67) | RARBMAPTSMN1; SMN2THRBNPC1 | |
| SCHEMBL9817621 | 1.00 | RARB (0.67) | RARBMAPTSMN1; SMN2THRBNPC1 | |
| SCHEMBL9817436 | 1.00 | RARB (0.67) | RARBMAPTSMN1; SMN2THRBNPC1 | |
| SCHEMBL9817517 | 1.00 | RARB (0.67) | RARBMAPTSMN1; SMN2THRBNPC1 | |
| SCHEMBL9817512 | 1.00 | RARB (0.67) | RARBMAPTSMN1; SMN2THRBNPC1 | |
| SCHEMBL9817453 | 1.00 | RARB (0.67) | RARBMAPTSMN1; SMN2THRBNPC1 | |
| SCHEMBL9817474 | 1.00 | RARB (0.67) | RARBMAPTSMN1; SMN2THRBNPC1 | |
| SCHEMBL9817531 | 1.00 | RARB (0.67) | RARBMAPTSMN1; SMN2THRBNPC1 | |
| SCHEMBL9817403 | 1.00 | RARB (0.67) | RARBMAPTSMN1; SMN2THRBNPC1 | |
| SCHEMBL9817770 | 0.99 | MAPT (0.67) | RARBMAPTSMN1; SMN2THRBNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5055221-A | Rapidly switching ferroelectric display element | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1991-10-08 | — | — | US | disclosed |