Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 6/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | RARA | P10276 | 1/20 | 0.47 |
| ▸ | MTOR | P42345 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
| ▸ | THRA | P10827 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9239286 | 0.97 | RARB (0.64) | RARBMAPTSMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL10701492 | 0.96 | RARB (0.62) | RARBMAPTSMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL9361459 | 0.96 | RARB (0.62) | RARBMAPTSMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL14525682 | 0.91 | RARB (0.56) | RARBMAPTSMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL9240202 | 0.91 | RARB (0.55) | RARBMAPTSMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL9237077 | 0.91 | RARB (0.55) | RARBMAPTSMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL9240084 | 0.91 | RARB (0.55) | RARBMAPTSMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL9236095 | 0.91 | RARB (0.55) | RARBMAPTSMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL9237462 | 0.91 | RARB (0.55) | RARBMAPTSMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL9236108 | 0.91 | RARB (0.55) | RARBMAPTSMN1; SMN2ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5055221-A | Rapidly switching ferroelectric display element | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1991-10-08 | — | — | US | disclosed |
| EP-0227717-B1 | NITROGEN-CONTAINING HETEROCYCLIC ESTERS | MERCK PATENT GmbH (DE) | 1990-04-25 | — | — | EP | disclosed |
| EP-0224579-B1 | SMECTIC LIQUID CRYSTALLINE PHASES | MERCK PATENT GmbH (DE) | 1990-01-24 | — | — | EP | disclosed |
| US-4820839-A | LIQUID CRYSTALS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1989-04-11 | — | — | US | disclosed |