Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 3/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | PDE1A | P54750 | 1/20 | 0.39 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.39 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.39 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | RARA | P10276 | 2/20 | 0.38 |
| ▸ | RARB | P10826 | 2/20 | 0.38 |
| ▸ | RARG | P13631 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9818169 | 1.00 | ESR1 (0.40) | ESR1ESR2PPARAPDE1APDE1B | |
| SCHEMBL31397826 | 0.82 | PPARA (0.54) | ESR1ESR2PPARAPDE1APDE1B | |
| SCHEMBL7907552 | 0.82 | PPARA (0.54) | ESR1ESR2PPARAPDE1APDE1B | |
| SCHEMBL31397827 | 0.82 | PPARA (0.54) | ESR1ESR2PPARAPDE1APDE1B | |
| SCHEMBL5493870 | 0.82 | PPARA (0.54) | ESR1ESR2PPARAPDE1APDE1B | |
| SCHEMBL9818192 | 0.82 | PPARA (0.54) | ESR1ESR2PPARAPDE1APDE1B | |
| SCHEMBL7908966 | 0.82 | PPARA (0.54) | ESR1ESR2PPARAPDE1APDE1B | |
| SCHEMBL7907564 | 0.80 | ESR1 (0.53) | ESR1ESR2PPARAPDE1APDE1B | |
| SCHEMBL7912738 | 0.80 | PPARA (0.46) | ESR1ESR2PPARAPDE1APDE1B | |
| SCHEMBL5495930 | 0.80 | PPARA (0.46) | ESR1ESR2PPARAPDE1APDE1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0271649-B1 | ESTERS OF 3-TERT.-BUTYL- OR 3-TERT.-BUTYL-5-ALKYL-4-HYDROXYPHENYL(ALKAN)OIC ACIDS WITH ETHOXYLATES OF BIS-(4- OR 2-HYDROXYPHENYL) ALKANES, OXIDES, SULFIDES AND SULFONES OF TRIS-(4-HYDROXYPHENYL) ALKANES AND OF 1,3,5-BIS-(4-HYDROXYPHENYL-ISOPROPYLIDENE) ARYLENE, THEIR PREPARATION AND USE AS STABILIZERS | HÜLS AKTIENGESELLSCHAFT (DE) | 1991-10-16 | — | — | EP | disclosed |
| US-4912249-A | Esters of 3-tert-butyl or 3-tert-butyl-5-alkyl-4-hydroxylphenyl(alkane) carboxylic acids | HUELS AKTIENGESELLSCHAFT (DE) | 1990-03-27 | — | — | US | disclosed |
| EP-0271649-A2 | Esters of 3-tert.-butyl- or 3-tert.-butyl-5-alkyl-4-hydroxyphenyl(alkan)oic acids with ethoxylates of bis-(4- or 2-hydroxyphenyl) alkanes, oxides, sulfides and sulfones of tris-(4-hydroxyphenyl) alkanes and of 1,3,5-bis-(4-hydroxyphenyl-isopropylidene) arylene, their preparation and use as stabilizers | HÜLS AKTIENGESELLSCHAFT (DE) | 1988-06-22 | — | — | EP | disclosed |