Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR1 | Q9Y271 | 3/20 | 0.54 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.54 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9818468 | 0.91 | CYSLTR1 (0.56) | CYSLTR1CYSLTR2 | |
| SCHEMBL9818395 | 0.91 | CYSLTR1 (0.56) | CYSLTR1CYSLTR2 | |
| SCHEMBL9818449 | 0.90 | CYSLTR2 (0.49) | CYSLTR1CYSLTR2 | |
| SCHEMBL6088514 | 0.90 | CYSLTR1 (0.53) | CYSLTR1CYSLTR2GPBAR1 | |
| SCHEMBL10421073 | 0.89 | CYSLTR1 (0.45) | CYSLTR1CYSLTR2GPBAR1 | |
| SCHEMBL7008709 | 0.89 | CYSLTR1 (0.57) | CYSLTR1CYSLTR2GPBAR1 | |
| SCHEMBL9818473 | 0.88 | CYSLTR1 (0.47) | CYSLTR1CYSLTR2GPBAR1 | |
| SCHEMBL7010321 | 0.87 | CYSLTR1 (0.60) | CYSLTR1CYSLTR2GPBAR1 | |
| SCHEMBL10536269 | 0.85 | CYSLTR2 (0.42) | CYSLTR1CYSLTR2 | |
| SCHEMBL6090364 | 0.85 | CYSLTR1 (0.50) | CYSLTR1CYSLTR2GPBAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5059610-A | QUINOLINE DERIVATIVES AND THEIR USE AS ANTAGONISTS OF LEUKOTRIENE D4 | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1991-10-22 | — | — | US | disclosed |