Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 5/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25430010 | 0.89 | TAAR1 (0.55) | CYP1A2CYP2D6CYP2C19CYP2C9NPSR1 | |
| SCHEMBL10263919 | 0.80 | NPSR1 (0.50) | CYP1A2CYP2D6CYP2C19CYP2C9NPSR1 | |
| SCHEMBL18112907 | 0.78 | CYP2C9 (0.55) | CYP1A2CYP2D6CYP2C19CYP2C9NPSR1 | |
| SCHEMBL19309401 | 0.77 | HTR2A (0.52) | CYP1A2CYP2D6CYP2C19CYP2C9NPSR1 | |
| SCHEMBL8591504 | 0.77 | HTR2A (0.52) | CYP1A2CYP2D6CYP2C19CYP2C9NPSR1 | |
| SCHEMBL22748280 | 0.77 | HTR2A (0.52) | CYP1A2CYP2D6CYP2C19CYP2C9NPSR1 | |
| SCHEMBL25359980 | 0.77 | CYP1A2 (0.50) | CYP1A2CYP2D6CYP2C19CYP2C9NPSR1 | |
| SCHEMBL30531106 | 0.77 | CYP1A2 (0.50) | CYP1A2CYP2D6CYP2C19CYP2C9NPSR1 | |
| SCHEMBL2475893 | 0.76 | CYP19A1 (0.48) | TAAR1KCNH2SIGMAR1 | |
| SCHEMBL10202985 | 0.76 | GRIN2D (0.44) | CYP1A2CYP2D6CYP2C19CYP2C9NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0308808-B1 | PROCESS FOR THE PREPARATION OF 2-FLUORO-5-ALLYL-DIPHENYL ETHERS | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-12-18 | — | — | EP | disclosed |
| EP-0308808-A1 | Process for the preparation of 2-fluoro-5-allyl-diphenyl ethers | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-03-29 | — | — | EP | disclosed |