Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 20/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10487420 | 1.00 | AKR1B1 (0.66) | AKR1B1 | |
| SCHEMBL9818912 | 1.00 | AKR1B1 (0.66) | AKR1B1 | |
| SCHEMBL10487800 | 0.84 | AKR1B1 (0.58) | AKR1B1 | |
| SCHEMBL27278870 | 0.81 | AKR1B1 (0.75) | AKR1B1 | |
| SCHEMBL10487452 | 0.80 | AKR1B1 (1.00) | AKR1B1 | |
| SCHEMBL10487431 | 0.78 | AKR1B1 (0.67) | AKR1B1 | |
| SCHEMBL27276603 | 0.77 | AKR1B1 (0.41) | AKR1B1 | |
| SCHEMBL10487455 | 0.76 | AKR1B1 (1.00) | AKR1B1 | |
| SCHEMBL9818973 | 0.75 | MAPK1 (0.40) | AKR1B1 | |
| SCHEMBL9818970 | 0.75 | MAPK1 (0.40) | AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0230379-B1 | CHROMAN- AND THIOCHROMAN-4-ACETIC ACIDS USEFUL IN THE TREATMENT OF DIABETIC COMPLICATIONS | PFIZER INC. (US) | 1991-04-03 | — | — | EP | disclosed |