Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 20/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9818918 | 1.00 | AKR1B1 (1.00) | AKR1B1 | |
| SCHEMBL8466089 | 1.00 | AKR1B1 (1.00) | AKR1B1 | |
| SCHEMBL10487523 | 0.96 | AKR1B1 (1.00) | AKR1B1 | |
| SCHEMBL1201316 | 0.91 | AKR1B1 (1.00) | AKR1B1 | |
| SCHEMBL6897149 | 0.91 | AKR1B1 (1.00) | AKR1B1 | |
| SCHEMBL9819259 | 0.91 | AKR1B1 (1.00) | AKR1B1 | |
| SCHEMBL10487408 | 0.90 | AKR1B1 (1.00) | AKR1B1 | |
| SCHEMBL27281009 | 0.88 | AKR1B1 (0.78) | AKR1B1 | |
| SCHEMBL10487405 | 0.85 | AKR1B1 (1.00) | AKR1B1 | |
| SCHEMBL10487503 | 0.85 | AKR1B1 (1.00) | AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0230379-B1 | CHROMAN- AND THIOCHROMAN-4-ACETIC ACIDS USEFUL IN THE TREATMENT OF DIABETIC COMPLICATIONS | PFIZER INC. (US) | 1991-04-03 | — | — | EP | disclosed |