Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 5/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9819000 | 1.00 | MAPT (0.41) | MAPTATMTP53L3MBTL1FFAR1 | |
| SCHEMBL7430025 | 0.75 | MAPT (0.44) | MAPTATMTP53L3MBTL1FFAR1 | |
| SCHEMBL31326550 | 0.74 | TP53 (0.41) | MAPTATMTP53L3MBTL1FFAR1 | |
| SCHEMBL21978182 | 0.74 | TP53 (0.41) | MAPTATMTP53L3MBTL1FFAR1 | |
| SCHEMBL11523163 | 0.71 | FFAR1 (0.43) | MAPTATMTP53L3MBTL1FFAR1 | |
| SCHEMBL9818881 | 0.69 | GLA (0.38) | TP53L3MBTL1FFAR1EGFRPOLB | |
| SCHEMBL9818765 | 0.69 | AKR1B1 (0.45) | MAPTTP53L3MBTL1FFAR1POLB | |
| SCHEMBL9818877 | 0.69 | GLA (0.38) | TP53L3MBTL1FFAR1EGFRPOLB | |
| SCHEMBL9818767 | 0.69 | AKR1B1 (0.45) | MAPTTP53L3MBTL1FFAR1POLB | |
| SCHEMBL11015326 | 0.68 | SLC6A2 (0.42) | TP53L3MBTL1FFAR1EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0230379-B1 | CHROMAN- AND THIOCHROMAN-4-ACETIC ACIDS USEFUL IN THE TREATMENT OF DIABETIC COMPLICATIONS | PFIZER INC. (US) | 1991-04-03 | — | — | EP | disclosed |