Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 2/20 | 0.77 |
| ▸ | TSHR | P16473 | 2/20 | 0.77 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cyclohexane SCHEMBL8538495 | 1.00 | USP2 (0.77) | USP2TSHRCA1CA2KDM4E | |
| Methanesulfonic Acid Methyl Ester SCHEMBL573583 | 0.88 | — | — | |
| Methanesulfonic Acid Methyl Ester SCHEMBL63290 | 0.88 | — | — | |
| Methanesulfonic Acid Methyl Ester SCHEMBL16060132 | 0.88 | USP2 (1.00) | USP2TSHRCA1CA2KDM4E | |
| Methanesulfonic Acid Methyl Ester SCHEMBL28902358 | 0.84 | — | — | |
| Methanesulfonic Acid Methyl Ester SCHEMBL30084031 | 0.84 | — | — | |
| Methanesulfonic Acid Methyl Ester SCHEMBL28884811 | 0.84 | — | — | |
| Methanesulfonic Acid Methyl Ester SCHEMBL5666257 | 0.84 | — | — | |
| Methanesulfonic Acid Methyl Ester SCHEMBL30823732 | 0.84 | — | — | |
| Methanesulfonic Acid Methyl Ester SCHEMBL28791572 | 0.84 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4987132-A | PLATELET ACTIVATING FACTOR ANTAGONISTS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1991-01-22 | — | — | US | disclosed |
| EP-0279681-A2 | Saturated heterocyclic carboxamide derivatives | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1988-08-24 | — | — | EP | disclosed |