Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 3/20 | 0.41 |
| ▸ | GBA1 | P04062 | 3/20 | 0.40 |
| ▸ | TLR2 | O60603 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | GNAI3 | P08754 | 2/20 | 0.33 |
| ▸ | GNAO1 | P09471 | 2/20 | 0.33 |
| ▸ | GNAI1 | P63096 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9820896 | 1.00 | PRCP (0.41) | PRCPGBA1TLR2ALDH1A1TDP1 | |
| SCHEMBL9820861 | 0.98 | PRCP (0.38) | PRCPGBA1TLR2ALDH1A1TDP1 | |
| SCHEMBL6844163 | 0.95 | GBA1 (0.39) | PRCPGBA1TLR2ALDH1A1TDP1 | |
| SCHEMBL9820936 | 0.84 | — | — | |
| SCHEMBL14673148 | 0.81 | — | — | |
| SCHEMBL14673092 | 0.81 | — | — | |
| SCHEMBL14672983 | 0.79 | — | — | |
| SCHEMBL22884638 | 0.78 | GBA1 (0.49) | GBA1ALDH1A1TDP1MEN1THRB | |
| SCHEMBL15100288 | 0.78 | — | — | |
| SCHEMBL6575454 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0296978-B1 | 1-BENZYL 2-OXO 5-ALKOXY PYRROLIDINE DERIVATIVES, PROCESS FOR THEIR PREPARATION, COMPOSITIONS CONTAINING THEM AND THEIR USE IN MEDICINES | ROUSSEL-UCLAF (FR) | 1991-09-11 | — | — | EP | disclosed |
| EP-0296978-A2 | 1-Benzyl 2-oxo 5-alkoxy pyrrolidine derivatives, process for their preparation, compositions containing them and their use in medicines | ROUSSEL-UCLAF (FR) | 1988-12-28 | — | — | EP | disclosed |