Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 2/20 | 0.38 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 4/20 | 0.35 |
| ▸ | HTR2B | P41595 | 4/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.34 |
| ▸ | HTR2A | P28223 | 2/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4973228 | 0.79 | KDM4E (0.41) | KDM1AHTR2CHTR2BALDH1A1RAB9A | |
| SCHEMBL4970927 | 0.79 | KDM4E (0.41) | KDM1AHTR2CHTR2BALDH1A1RAB9A | |
| SCHEMBL4970930 | 0.79 | KDM4E (0.41) | KDM1AHTR2CHTR2BALDH1A1RAB9A | |
| SCHEMBL5584663 | 0.77 | KDM1A (0.42) | BRD4KDM1AMAP1LC3BHTR2CHTR2B | |
| SCHEMBL30626968 | 0.77 | KDM1A (0.45) | BRD4KDM1AMAP1LC3BHTR2CHTR2B | |
| SCHEMBL2530746 | 0.77 | KDM1A (0.45) | BRD4KDM1AMAP1LC3BHTR2CHTR2B | |
| SCHEMBL10046437 | 0.74 | KDM1A (0.50) | BRD4KDM1AMAP1LC3BHTR2CHTR2B | |
| SCHEMBL29427088 | 0.74 | KDM1A (0.50) | BRD4KDM1AMAP1LC3BHTR2CHTR2B | |
| SCHEMBL240786 | 0.73 | SLC18A3 (0.42) | CYP2D6 | |
| SCHEMBL2303598 | 0.73 | SLC18A3 (0.42) | CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5017724-A | Antihypoxic, CNS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1991-05-21 | — | — | US | disclosed |
| EP-0267024-B1 | HYDROFLUORENE DERIVATIVES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1991-05-02 | — | — | EP | disclosed |
| EP-0267024-A2 | Hydrofluorene derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1988-05-11 | — | — | EP | disclosed |