Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 4/20 | 0.39 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 4/20 | 0.37 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.36 |
| ▸ | PTGER2 | P43116 | 3/20 | 0.36 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.36 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 3/20 | 0.35 |
| ▸ | RORC | P51449 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11700667 | 0.82 | KDM1A (0.51) | KDM1ASMN1; SMN2MAOAMAOB | |
| SCHEMBL15767640 | 0.82 | KDM1A (0.51) | KDM1ASMN1; SMN2MAOAMAOB | |
| SCHEMBL1943935 | 0.82 | KDM1A (0.51) | KDM1ASMN1; SMN2MAOAMAOB | |
| SCHEMBL3739337 | 0.81 | KDM1A (0.40) | KDM1ARCOR1LMNASMN1; SMN2MAOA | |
| SCHEMBL1000359 | 0.81 | KDM1A (0.51) | KDM1ARCOR1LMNATSHRSMN1; SMN2 | |
| SCHEMBL15766918 | 0.81 | KDM1A (0.51) | KDM1ARCOR1LMNATSHRSMN1; SMN2 | |
| SCHEMBL15766917 | 0.81 | KDM1A (0.51) | KDM1ARCOR1LMNATSHRSMN1; SMN2 | |
| SCHEMBL7077980 | 0.81 | KDM1A (0.51) | KDM1ARCOR1LMNACYP2C9TSHR | |
| SCHEMBL7070199 | 0.79 | KMT2A (0.45) | LMNACYP2C9TSHRBLMPPARA | |
| SCHEMBL9820886 | 0.79 | KDM1A (0.35) | KDM1ARCOR1LMNACYP2C9TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0188887-B1 | TERTIARY AMINE COMPOUNDS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-05-02 | — | — | EP | disclosed |
| EP-0188887-A1 | Tertiary amine compounds | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1986-07-30 | — | — | EP | disclosed |