Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | ADRA1D | P25100 | 6/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 6/20 | 0.42 |
| ▸ | ADRA1B | P35368 | 6/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.40 |
| ▸ | CECR2 | Q9BXF3 | 1/20 | 0.40 |
| ▸ | NQO2 | P16083 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9628927 | 0.94 | TSHR (0.67) | TSHRHTTADRA1DADRA1AADRA1B | |
| SCHEMBL11105997 | 0.91 | TSHR (0.63) | TSHRHTTKMT2ALMNAATAD2 | |
| SCHEMBL11112926 | 0.91 | TSHR (0.63) | TSHRHTTKMT2ALMNAATAD2 | |
| SCHEMBL11110025 | 0.91 | TSHR (0.63) | TSHRHTTKMT2ALMNAATAD2 | |
| SCHEMBL21389251 | 0.84 | HTT (0.54) | TSHRHTTADRA1DADRA1AADRA1B | |
| SCHEMBL1532937 | 0.82 | TSHR (0.85) | TSHRHTTKMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL20183073 | 0.81 | TSHR (0.56) | TSHRHTTADRA1DADRA1AADRA1B | |
| SCHEMBL24263535 | 0.80 | TSHR (0.89) | TSHRHTTKMT2ALMNAL3MBTL1 | |
| SCHEMBL10642187 | 0.80 | HTT (0.51) | TSHRHTTADRA1DADRA1AADRA1B | |
| SCHEMBL23847771 | 0.80 | HTT (0.51) | TSHRHTTADRA1DADRA1AADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5021568-A | Lactam-1-acetic acid carbalkoxymethyl esters and method for preparing same | SHIPOV ALEXANDR G (SU) | 1991-06-04 | — | — | US | disclosed |
| US-4162325-A | PHARMACEUTICAL ACTIVITY ON THE MNEMIC PROCESSES | UCB, SOCIETE ANONYME (BE) | 1979-07-24 | — | — | US | disclosed |