⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL204060 | 0.80 | — | — | |
| SCHEMBL8773940 | 0.78 | — | — | |
| SCHEMBL1230616 | 0.76 | SLC22A2 (0.31) | — | |
| SCHEMBL8189 | 0.76 | — | — | |
| SCHEMBL1068247 | 0.71 | — | — | |
| SCHEMBL23044817 | 0.71 | — | — | |
| SCHEMBL6053192 | 0.71 | — | — | |
| SCHEMBL4820255 | 0.71 | — | — | |
| Water SCHEMBL4709834 | 0.71 | — | — | |
| SCHEMBL6344816 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0240264-B1 | IMPROVED PROCESS FOR PREPARING MACROLIDE DERIVATIVES | ELI LILLY AND COMPANY (US) | 1991-08-28 | — | — | EP | disclosed |
| EP-0188373-B1 | MACROLIDE DERIVATIVES | ELI LILLY AND COMPANY (US) | 1989-11-08 | — | — | EP | disclosed |
| EP-0240264-A2 | Improved process for preparing macrolide derivatives | ELI LILLY AND COMPANY (US) | 1987-10-07 | — | — | EP | disclosed |
| EP-0103465-B1 | 20-AMINO MACROLIDE DERIVATIVES | ELI LILLY AND COMPANY (US) | 1986-09-10 | — | — | EP | disclosed |
| EP-0188373-A2 | Macrolide derivatives | ELI LILLY AND COMPANY (US) | 1986-07-23 | — | — | EP | disclosed |