Butyric Acid

Butyric Acid

SCHEMBL9824028

CC(C)=O.CCCC(=O)O.c1ccccc1

nearest known ligand 0.77

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FFAR3 O14843 1/20 0.77
HDAC3 O15379 1/20 0.77
HDAC1 Q13547 1/20 0.77
HDAC2 Q92769 1/20 0.77
HDAC8 Q9BY41 1/20 0.77
AKR1B1 P15121 1/20 0.50
GPR84 Q9NQS5 7/20 0.48
PPARG P37231 7/20 0.48
PPARD Q03181 7/20 0.48
PPARA Q07869 7/20 0.48
HDAC11 Q96DB2 5/20 0.48
TSHR P16473 4/20 0.48
PTPN1 P18031 3/20 0.48
ALDH1A1 P00352 2/20 0.48
TLR2 O60603 2/20 0.48
TDP1 Q9NUW8 2/20 0.48
FABP4 P15090 2/20 0.48
SLC22A6 Q4U2R8 1/20 0.48
SLC22A8 Q8TCC7 1/20 0.48
MEN1 O00255 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Butyric Acid SCHEMBL11818808 0.94 FFAR3 (0.77) FFAR3HDAC3HDAC1HDAC2HDAC8
Butyric Acid SCHEMBL31286426 0.94 FFAR3 (0.87) FFAR3HDAC3HDAC1HDAC2HDAC8
Butyric Acid SCHEMBL28594182 0.94 FFAR3 (0.87) FFAR3HDAC3HDAC1HDAC2HDAC8
Butyric Acid SCHEMBL11626724 0.94 FFAR3 (0.87) FFAR3HDAC3HDAC1HDAC2HDAC8
Butyric Acid SCHEMBL9390075 0.94 FFAR3 (0.87) FFAR3HDAC3HDAC1HDAC2HDAC8
Butyric Acid SCHEMBL3241752 0.94 FFAR3 (0.87) FFAR3HDAC3HDAC1HDAC2HDAC8
Butyric Acid SCHEMBL11626727 0.94 FFAR3 (0.87) FFAR3HDAC3HDAC1HDAC2HDAC8
Butyric Acid SCHEMBL1994703 0.94 FFAR3 (0.87) FFAR3HDAC3HDAC1HDAC2HDAC8
Butyric Acid SCHEMBL28519333 0.91 FFAR3 (0.81) FFAR3HDAC3HDAC1HDAC2HDAC8
Butyric Acid SCHEMBL11484161 0.91 FFAR3 (0.81) FFAR3HDAC3HDAC1HDAC2HDAC8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0199963-B1 ETHOSUXIMIDE ASSAY TRACERS, IMMUNOGENS AND ANTIBODIES ABBOTT LABORATORIES (US) 1991-10-23 EP disclosed
EP-0199963-A1 Ethosuximide assay tracers, immunogens and antibodies ABBOTT LABORATORIES (US) 1986-11-05 EP disclosed